Evidence map›Paper›PMID 29296565›Full record

ArticleIntegrative medicine research2017

Optimization of ultrasound-assisted extraction of glycyrrhizic acid from licorice using response surface methodology.

Seol Jang, A Yeong Lee, A Reum Lee, Goya Choi, Ho Kyoung Kim

Abstract read
In one paragraph

Article in Integrative medicine research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Optimization of Extraction Process for Flavonoids fromMolecules (Basel, Switzerland) · 2026
    Article
  2. Foods (Basel, Switzerland) · 2025
    Article
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  8. Article
  9. Efficiency ofEvidence-based complementary and alternative medicine : eCAM · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Seol JangMibyeong Research Center, Korea Institute of Oriental Medicine, Daejeon, Korea.
A Yeong LeeK-herb Research Center, Korea Institute of Oriental Medicine, Daejeon, Korea.
A Reum LeeK-herb Research Center, Korea Institute of Oriental Medicine, Daejeon, Korea.
Goya ChoiK-herb Research Center, Korea Institute of Oriental Medicine, Daejeon, Korea.
Ho Kyoung KimMibyeong Research Center, Korea Institute of Oriental Medicine, Daejeon, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe present study optimized ultrasound-assisted extraction conditions to maximize extraction yields of glycyrrhizic acid from licorice.

methodsThe optimal extraction temperature (X

resultsStatistical analyses revealed that three variables and the quadratic of X

conclusionThe experimental values agreed with those predicted by RSM models, thus indicating the suitability of the model employed and the success of RSM in optimizing the extraction conditions.

Indexed as

glycyrrhizic acidlicoriceoptimizationresponse surface methodologyultrasound-assisted extraction

Identifiers

PMID29296565
PMCPMC5741391

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.