Evidence map›Paper›PMID 29296525›Full record

ArticleOncoimmunology

Langerhans-type dendritic cells electroporated with TRP-2 mRNA stimulate cellular immunity against melanoma: Results of a phase I vaccine trial.

David J Chung, Richard D Carvajal, Michael A Postow, Sneh Sharma, Katherine B Pronschinske, Justin A Shyer, Shahnaz Singh-Kandah, Mark A Dickson, Sandra P D'Angelo, Jedd D Wolchok and 1 more

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Langerhans Cells-Revising Their Role in Skin Pathologies.Journal of personalized medicine · 2022
    Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

David J ChungLaboratory of Cellular Immunobiology, Memorial Sloan Kettering Cancer Center, New York, NY.
Richard D CarvajalMelanoma and Immunotherapeutics Service, Memorial Sloan Kettering Cancer Center, New York, NY.
Michael A PostowMelanoma and Immunotherapeutics Service, Memorial Sloan Kettering Cancer Center, New York, NY.
Sneh SharmaLaboratory of Cellular Immunobiology, Memorial Sloan Kettering Cancer Center, New York, NY.
Katherine B PronschinskeLaboratory of Cellular Immunobiology, Memorial Sloan Kettering Cancer Center, New York, NY.
Justin A ShyerLaboratory of Cellular Immunobiology, Memorial Sloan Kettering Cancer Center, New York, NY.
Shahnaz Singh-KandahMelanoma and Immunotherapeutics Service, Memorial Sloan Kettering Cancer Center, New York, NY.
Mark A DicksonSarcoma Medical Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY.
Sandra P D'AngeloSarcoma Medical Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY.
Jedd D WolchokMelanoma and Immunotherapeutics Service, Memorial Sloan Kettering Cancer Center, New York, NY.
James W YoungLaboratory of Cellular Immunobiology, Memorial Sloan Kettering Cancer Center, New York, NY.
Memorial Sloan Kettering Cancer Center · USCornell University · USRockefeller University · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Elisa de Stanchina · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cancer vaccinesclinical immunologyLangerhans-type dendritic cellmelanomaphase I trial

Identifiers

PMID29296525
PMCPMC5739582
OpenAlexW2753296174

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.