Evidence map›Paper›PMID 29296507›Full record

ArticleBiomedical optics express2017

Periodic microstructures of blood capillaries revealed by synchrotron X-ray multi-resolution microscopic analysis.

Shengkun Yao, Yunbing Zong, Xu Huang, Yang Liu, Ningqiang Gong, Jianhua Zhang, Ziqing Li, Feng Cao, Xiangcheng Wang, Xing-Jie Liang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Shengkun YaoSchool of Physical Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Yunbing ZongState Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, China.
Xu HuangDepartment of Cardiology, Chinese PLA General Hospital, Beijing 100853, China.
Yang LiuSchool of Physical Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Ningqiang GongLaboratory of Controllable Nanopharmaceuticals, Chinese Academy of Sciences (CAS) Center for Excellence in Nanoscience; and CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology of China, No. 11, First North Road Zhongguangcun, Beijing 100190, China.
Jianhua ZhangSchool of Physical Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Ziqing LiState Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, China.
Feng CaoDepartment of Cardiology, Chinese PLA General Hospital, Beijing 100853, China.
Xiangcheng WangDepartment of Data and Business Analysis Product, Inspur International Ltd., Jinan 250101, China.
Xing-Jie LiangLaboratory of Controllable Nanopharmaceuticals, Chinese Academy of Sciences (CAS) Center for Excellence in Nanoscience; and CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology of China, No. 11, First North Road Zhongguangcun, Beijing 100190, China.
Huaidong JiangSchool of Physical Science and Technology, ShanghaiTech University, Shanghai 201210, China.
State Key Laboratory of Crystal MaterialsChinese PLA General Hospital · CNNational Center for Nanoscience and Technology · CNInspur (China) · CNShanghaiTech University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular diseases are closely related to structural blood capillaries lesions. Herein, microscopic investigations of mouse blood capillaries were performed at multiple spatial resolution by using synchrotron X-ray in-line phase contrast tomography and scanning transmission X-ray microscopy (STXM). The chemically fixed blood capillaries without any contrast agents were selected. For the first time, a periodic bamboo-shaped structure was observed at nanoscale resolution by STXM, and the three-dimensional tomographic slices at sub-micrometer resolution further confirmed the periodic wave profile of the blood capillaries. Then, a periodic microstructural model was suggested based on the microscopic images. By using high-performance imaging techniques, this work provides a better understanding of the relationship between the structure and function of blood capillaries, will be helpful in elucidating the causes of cardiovascular system diseases.

Indexed as

(110.6955) Tomographic imaging(170.0180) Microscopy(170.3880) Medical and biological imaging(170.7440) X-ray imaging(180.7460) X-ray microscopy

Identifiers

PMID29296507
PMCPMC5745122
OpenAlexW2773960008

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.