ArticleBiomedical optics express2017
Structured illumination microscopy for dual-modality 3D sub-diffraction resolution fluorescence and refractive-index reconstruction.
Article in Biomedical optics express, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Multimodal holotomography for volumetric monitoring of host-pathogen interactions.Biomedical engineering online · 2026Article
- A correlative quantitative phase contrast and fluorescence super-resolution microscope for imaging molecules in their cellular context.bioRxiv : the preprint server for biology · 2025Article
- Fourier synthesis optical diffraction tomography for kilohertz rate volumetric imaging.Science advances · 2025Article
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- Multi-modal transport of intensity diffraction tomography microscopy with an electrically tunable lens [Invited].Biomedical optics express · 2025Article
- Utilizing quantitative phase microscopy to localize fluorescence in three dimensions via the transport of intensity equation.Optics letters · 2024Article
- Quantitative phase imaging based on holography: trends and new perspectives.Light, science & applications · 2024Review
- Recent Advances and Current Trends in Transmission Tomographic Diffraction Microscopy.Sensors (Basel, Switzerland) · 2024Review
- Review
- Single-Shot 3D Topography of Transmissive and Reflective Samples with a Dual-Mode Telecentric-Based Digital Holographic Microscope.Sensors (Basel, Switzerland) · 2022Article
- Robust Fourier ptychographic microscopy via a physics-based defocusing strategy for calibrating angle-varied LED illumination.Biomedical optics express · 2022Article
- High-speed multiview imaging approaching 4pi steradians using conic section mirrors: theoretical and practical considerations.Journal of the Optical Society of America. A, Optics, image science, and vision · 2021Article
- Common-path intrinsically achromatic optical diffraction tomography.Biomedical optics express · 2021Article
- Spatial light interference microscopy: principle and applications to biomedicine.Advances in optics and photonics · 2021Article
- Multicolor structured illumination microscopy and quantitative control of polychromatic light with a digital micromirror device.Biomedical optics express · 2021Article
- Optical coherence refraction tomography.Nature photonics · 2019Article
- High-resolution 3D refractive index microscopy of multiple-scattering samples from intensity images.Optica · 2019Article
- Speckle-structured illumination for 3D phase and fluorescence computational microscopy.Biomedical optics express · 2019Article
- Low-coherent optical diffraction tomography by angle-scanning illumination.Journal of biophotonics · 2019Article
- Computational structured illumination for high-content fluorescence and phase microscopy.Biomedical optics express · 2019Article
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4 authors.
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Abstract
Though structured illumination (SI) microscopy is a popular imaging technique conventionally associated with fluorescent super-resolution, recent works have suggested its applicability towards sub-diffraction resolution coherent imaging with quantitative endogenous biological contrast. Here, we demonstrate that SI can efficiently integrate together the principles of fluorescent super-resolution and coherent synthetic aperture to achieve 3D dual-modality sub-diffraction resolution, fluorescence and refractive-index (RI) visualizations of biological samples. We experimentally demonstrate this framework by introducing a SI microscope capable of 3D sub-diffraction resolution fluorescence and RI imaging, and verify its biological visualization capabilities by experimentally reconstructing 3D RI/fluorescence visualizations of fluorescent calibration microspheres as well as alveolar basal epithelial adenocarcinoma (A549) and human colorectal adenocarcinmoa (HT-29) cells, fluorescently stained for F-actin. This demonstration may suggest SI as an especially promising imaging technique to enable future biological studies that explore synergistically operating biophysical/biochemical and molecular mechanisms at sub-diffraction resolutions.
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