Evidence map›Paper›PMID 29296479›Full record

ArticleBiomedical optics express2017

Two step imaging reconstruction using truncated pseudoinverse as a preliminary estimate in ultrasound guided diffuse optical tomography.

K M Shihab Uddin, Atahar Mostafa, Mark Anastasio, Quing Zhu

Abstract read
In one paragraph

Article in Biomedical optics express, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Convolutional-transformer fusion of ultrasound and diffuse optical tomography for breast lesion classification.Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

K M Shihab UddinBiomedical Engineering Department, Washington University in St. Louis, 1 Brookings Dr, St. Louis, MO 63130, USA.
Atahar MostafaBiomedical Engineering Department, Washington University in St. Louis, 1 Brookings Dr, St. Louis, MO 63130, USA.
Mark AnastasioBiomedical Engineering Department, Washington University in St. Louis, 1 Brookings Dr, St. Louis, MO 63130, USA.
Quing ZhuBiomedical Engineering Department, Washington University in St. Louis, 1 Brookings Dr, St. Louis, MO 63130, USA.

Funding

Near Infrared Diffused Light Imaging with Ultrasound Guidance: Predicting Neoadjuvant Chemotherapy ResponseR01EB002136 · NIBIB · WASHINGTON UNIVERSITY · PI ZHU, QUING · 2003 to 2016
$3.4M
NIBIB NIH HHS R01 EB002136
6 · The paper itself

Abstract

Due to the correlated nature of diffused light, the problem of reconstructing optical properties using diffuse optical tomography (DOT) is ill-posed. US-, MRI- or x-ray-guided DOT approaches can reduce the total number of parameters to be estimated and improve optical reconstruction accuracy. However, when the target volume is large, the number of parameters to estimate can exceed the number of measurements, resulting in an underdetermined imaging model. In such cases, accurate image reconstruction is difficult and regularization methods should be employed to obtain a useful solution. In this manuscript, a simple two-step reconstruction method that can produce useful image estimates in DOT is proposed and investigated. In the first step, a truncated Moore-Penrose Pseudoinverse solution is computed to obtain a preliminary estimate of the image that can be reliably determined from the measured data; subsequently, this preliminary estimate is incorporated into the design of a penalized least squares estimator that is employed to compute the final image estimate. By use of phantom data, the proposed method was demonstrated to yield more accurate images than those produced by conventional reconstruction methods. The method was also evaluated with clinical data that included 10 benign and 10 malignant cases. The capability of reconstructing high contrast malignant lesions was demonstrated to be improved by use of the proposed method.

Indexed as

(170.0170) Medical optics and biotechnology(170.1610) Clinical applications(170.3010) Image reconstruction techniques(170.3660) Light propagation in tissues(170.3880) Medical and biological imaging(170.6935) Tissue characterization

Identifiers

PMID29296479
PMCPMC5745094

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.