Evidence map›Paper›PMID 29296474›Full record

ArticleBiomedical optics express2017

Correlative imaging of biological tissues with apertureless scanning near-field optical microscopy and confocal laser scanning microscopy.

Stefan G Stanciu, Denis E Tranca, Radu Hristu, George A Stanciu

Abstract read
In one paragraph

Article in Biomedical optics express, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Stefan G StanciuCenter for Microscopy-Microanalysis and Information Processing, University Politehnica of Bucharest, Bucharest, 060042, Romania.
Denis E TrancaCenter for Microscopy-Microanalysis and Information Processing, University Politehnica of Bucharest, Bucharest, 060042, Romania.
Radu HristuCenter for Microscopy-Microanalysis and Information Processing, University Politehnica of Bucharest, Bucharest, 060042, Romania.
George A StanciuCenter for Microscopy-Microanalysis and Information Processing, University Politehnica of Bucharest, Bucharest, 060042, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Apertureless scanning near-field optical microscopy (ASNOM) has attracted considerable interest over the past years as a result of its valuable contrast mechanisms and capabilities for optical resolutions in the nanoscale range. However, at this moment the intersections between ASNOM and the realm of bioimaging are scarce, mainly due to data interpretation difficulties linked to the limited body of work performed so far in this field and hence the reduced volume of supporting information. We propose an imaging approach that holds significant potential for alleviating this issue, consisting of correlative imaging of biological specimens using a multimodal system that incorporates ASNOM and confocal laser scanning microscopy (CLSM), which allows placing near-field data into a well understood context of anatomical relevance. We demonstrate this approach on zebrafish retinal tissue. The proposed method holds important implications for the in-depth understanding of biological items through the prism of ASNOM and CLSM data complementarity.

Indexed as

(170.0110) Imaging systems(170.6935) Tissue characterization(180.1790) Confocal microscopy(180.4243) Near-field microscopy

Identifiers

PMID29296474
PMCPMC5745089

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.