ArticleJournal of radiosurgery and SBRT2013
Intensity-modulated fractionated stereotactic radiotherapy with reduced margin for high grade gliomas: dosimetric analysis of sparing optic nerve & chiasm.
Article in Journal of radiosurgery and SBRT, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 citations in OpenAlex.
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to evaluate the potential advantage of intensity modulation fractionated stereotactic radiotherapy (IM-FSRT) for sparing the optic nerve and chiasm in the management of anaplastic astrocytoma (AA) or glioblastoma (GBM). Clinical data of 16 patients with high grade gliomas were retrospectively reviewed. All patients had tumors close to the optic chiam that prohibited the full dose radiation therapy. The patients were treated with either IM-FSRT in conjunction with external beam radiation or IM-FSRT only to a total dose of 60 Gy. The final dosimetric analysis was performed. The estimated average maximum optic nerve and chiasm dose 48.6±5.0 Gy (range, 34.2-55.9). Conformity index reached as high as 0.98, and inhomogeneity coefficient was low enough to deliver the prescribed radiation dose. IM-FSRT showed excellent dose conformality to the target volume with superior normal tissue sparing effect. High precision therapy such as IM-FSRT could be a reliable treatment technique for the patients with AA or GBM for a maximal sparing of optic apparatus.
Indexed as
Identifiers
29296373PMC5658840W2973688050What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.