Evidence map›Paper›PMID 29296341›Full record

ArticleJournal of radiosurgery and SBRT2012

Stereotactic radiosurgery and radiotherapy for meningiomas: biomarker predictors of patient outcome and response to therapy.

Randy L Jensen, Lindsey Minshew, Annabelle F Shrieve, Nan Hu, Dennis C Shrieve

Open access · greenAbstract read
In one paragraph

Article in Journal of radiosurgery and SBRT, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Radiobiology of stereotactic radiotherapy.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2022
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Randy L JensenDepartment of Neurosurgery, University of Utah Health Sciences Center, Salt Lake City, Utah, 84132, USA.
Lindsey MinshewDepartment of Neurosurgery, University of Utah Health Sciences Center, Salt Lake City, Utah, 84132, USA.
Annabelle F ShrieveHuntsman Cancer Hospital, Salt Lake City, Utah, 84112, USA.
Nan HuDepartment of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, Utah, 84132, USA.
Dennis C ShrieveDepartment of Radiation Oncology, University of Utah Health Sciences Center, Salt Lake City, Utah, 84132, USA.
University of Utah · USHuntsman (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although surgery has traditionally been the primary treatment of meningiomas, stereotactic radiosurgery (SRS) and radiotherapy (SRT) techniques have become a standard part of the treatment approach to intracranial meningiomas. For incompletely resected or inoperable benign meningiomas, SRT and SRS can provide excellent 5-year tumor control rates in 90% to 95% of benign meningioma cases. The current data on prognostic factors in meningioma SRT and SRS treatment outcomes are sparse. Our study aims to define prognostic factors that may help determine meningioma SRT and SRS treatment outcomes. Outcomes of 162 patients with 166 intracranial meningiomas treated with SRT (80 treatments) or SRS (92 treatments) were examined. Patient characteristics and tumor hypoxia-regulated biomarkers were correlated with tumor local control and overall survival. Median follow-up was 52 months, with median tumor volumes and treatment doses of 2.72 cm

Indexed as

biomarkersfractionated radiotherapymeningiomasprognosisRadiationrecurrencestereotactic radiosurgerysurvival

Identifiers

PMID29296341
PMCPMC5658852
OpenAlexW3024316617

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.