ReviewJournal of nutritional science2017
Nutrients and perinatal depression: a systematic review.
Review in Journal of nutritional science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Role of Vitamin D in Preventing and Treating Selected Extraskeletal Diseases-An Umbrella Review.Nutrients · 2020Pooled it
- Nutrition-sensitive agriculture programme impacts women's mental health via food security in rural Bangladesh.BMJ global health · 2026Trial
- Trial
- Understanding modifiable caregiver factors contributing to child development among young children in rural Malawi.Maternal & child nutrition · 2024Trial
- Sensory Preferences Influencing the Likelihood That African American Pregnant Women Will Consume Nutrient-Dense, Anti-Inflammatory Foods.International journal of environmental research and public health · 2026Article
- African American Food Environments and Anti-Inflammatory Intake in Pregnancy.International journal of environmental research and public health · 2026Article
- Caregiver Nutrition and Nurturing Care: A Scoping Review.Maternal & child nutrition · 2025Article
- Folate intake,The British journal of nutrition · 2025Article
- Predicting Prenatal Depression and Assessing Model Bias Using Machine Learning Models.Biological psychiatry global open science · 2024Article
- Article
- A network analysis of nutritional markers and maternal perinatal mental health in the French EDEN cohort.BMC pregnancy and childbirth · 2023Article
- Postpartum depression: aetiology, pathogenesis and the role of nutrients and dietary supplements in prevention and management.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023Review
- A Probiotic Intervention With Bifidobacterium longum NCC3001 on Perinatal Mood Outcomes (PROMOTE Study): Protocol for a Decentralized Randomized Controlled Trial.JMIR research protocols · 2023Article
- Review
- Systematic evidence and gap map of research linking food security and nutrition to mental health.Nature communications · 2022Article
- Maternal Mental Health in Late Pregnancy and Longitudinal Changes in Postpartum Serum Vitamin B-12, Homocysteine, and Milk B-12 Concentration Among Brazilian Women.Frontiers in nutrition · 2022Article
- Food security mediates the decrease in women's depressive symptoms in a participatory nutrition-sensitive agroecology intervention in rural Tanzania.Public health nutrition · 2021Article
- Global Mental Health and Nutrition: Moving Toward a Convergent Research Agenda.Frontiers in public health · 2021Review
- Prevalence of perinatal depression among Japanese men: a meta-analysis.Annals of general psychiatry · 2020Review
- Comorbid Anxiety and Depression among Pregnant Pakistani Women: Higher Rates, Different Vulnerability Characteristics, and the Role of Perceived Stress.International journal of environmental research and public health · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pregnancy and lactation deplete nutrients essential to the neurotransmission system. This may be one reason for the increased risk of depression during the perinatal period. The objective of the present review was to systematically review the literature and summarise evidence on whether blood nutrient levels influence the risk of perinatal depression. PubMed, EMBASE and CINAHL databases were searched for studies of any design. A total of twenty-four articles of different designs were included, representing 14 262 subjects. We extracted data on study population, depression prevalence, nutrients examined, deficiency prevalence, timing of assessment, reporting, analysis strategy and adjustment factors. In all, fourteen studies found associations of perinatal depression with lower levels of folate, vitamin D, Fe, Se, Zn, and fats and fatty acids, while two studies found associations between perinatal depression and higher nutrient levels, and eight studies found no evidence of an association. Only ten studies had low risk of bias. Given the methodological limitations and heterogeneity of study approaches and results, the evidence for a causal link between nutritional biomarkers and perinatal depression is still inconclusive. High-quality studies in deficient populations are needed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.