Evidence map›Paper›PMID 29296124›Full record

ArticleClinical epigenetics2017

Isabela Martins Gonzaga, Sheila Coelho Soares Lima, Marina Chianello Nicolau, Pedro Nicolau-Neto, Nathalia Meireles da Costa, Tatiana de Almeida Simão, Hector Hernandez-Vargas, Zdenko Herceg, Luis Felipe Ribeiro Pinto

Open access · goldAbstract read
In one paragraph

Article in Clinical epigenetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. C/EBPα Epigenetically ModulatesFrontiers in immunology · 2022
    Article
  7. Article
  8. Article
  9. Gastrokine 2 Regulates the Antitumor Effect of JAK2/STAT3 Pathway in Gastric Cancer.Evidence-based complementary and alternative medicine : eCAM · 2021
    Article
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Isabela Martins GonzagaPrograma de Carcinogênese Molecular, Instituto Nacional de Câncer, Coordenação de Pesquisa, Rua André Cavalcanti, 37-6° andar, Bairro de Fátima, Rio de Janeiro, Rio de Janeiro CEP: 20231-050 Brazil.
Sheila Coelho Soares LimaPrograma de Carcinogênese Molecular, Instituto Nacional de Câncer, Coordenação de Pesquisa, Rua André Cavalcanti, 37-6° andar, Bairro de Fátima, Rio de Janeiro, Rio de Janeiro CEP: 20231-050 Brazil.
Marina Chianello NicolauPrograma de Carcinogênese Molecular, Instituto Nacional de Câncer, Coordenação de Pesquisa, Rua André Cavalcanti, 37-6° andar, Bairro de Fátima, Rio de Janeiro, Rio de Janeiro CEP: 20231-050 Brazil.
Pedro Nicolau-NetoPrograma de Carcinogênese Molecular, Instituto Nacional de Câncer, Coordenação de Pesquisa, Rua André Cavalcanti, 37-6° andar, Bairro de Fátima, Rio de Janeiro, Rio de Janeiro CEP: 20231-050 Brazil.
Nathalia Meireles da CostaPrograma de Carcinogênese Molecular, Instituto Nacional de Câncer, Coordenação de Pesquisa, Rua André Cavalcanti, 37-6° andar, Bairro de Fátima, Rio de Janeiro, Rio de Janeiro CEP: 20231-050 Brazil.
Tatiana de Almeida SimãoDepartamento de Bioquímica, Instituto de Biologia Roberto Alcantara Gomes, Universidade do Estado do Rio de Janeiro, Av. 28 de Setembro 87 fundos, Vila Isabel, Rio de Janeiro, CEP: 20551-013 Brazil.
Hector Hernandez-VargasEpigenetics Group, Section of Mechanisms of Carcinogenesis, International Agency for Research on Cancer, 150 Cours Albert Thomas, 69372, CEDEX 08 Lyon, France.
Zdenko HercegEpigenetics Group, Section of Mechanisms of Carcinogenesis, International Agency for Research on Cancer, 150 Cours Albert Thomas, 69372, CEDEX 08 Lyon, France.
Luis Felipe Ribeiro PintoPrograma de Carcinogênese Molecular, Instituto Nacional de Câncer, Coordenação de Pesquisa, Rua André Cavalcanti, 37-6° andar, Bairro de Fátima, Rio de Janeiro, Rio de Janeiro CEP: 20231-050 Brazil.
Instituto Nacional do Câncer · BRCentre International de Recherche sur le Cancer · FRUniversidade do Estado do Rio de Janeiro · BR

Funding

World Health Organization 001
6 · The paper itself

Abstract

Background: Esophageal squamous cell carcinoma (ESCC) is one of the 10 most incident cancer types in the world, and it is mainly associated with tobacco and alcohol consumption. ESCC mortality rates stand very close to its incidence, which is a direct consequence of a late diagnosis and an inefficient treatment. Although this scenery is quite alarming, the major molecular alterations that drive this carcinogenesis process remain unclear. We have previously shown through the first ESCC methylome analysis that Results: Analysis of Conclusions: This study shows that

Indexed as

DNA MethylationDown-RegulationAdultAgedAzacitidineBiomarkers, TumorCarcinoma, Squamous CellCell Line, TumorDecitabineEarly Detection of CancerEpigenesis, GeneticEsophageal NeoplasmsEsophageal Squamous Cell CarcinomaFemaleGene Expression Regulation, NeoplasticHumansAzacitidineBiomarkers, TumorDecitabineTFF1 protein, humanTrefoil Factor-1BiomarkerDNA methylationEsophageal cancerEsophageal squamous cell carcinomaTFF1Trefoil factors

Identifiers

PMID29296124
PMCPMC5738900
OpenAlexW2778086680

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.