Evidence map›Paper›PMID 29296121›Full record

ArticleBiotechnology for biofuels2017

Isolation, phenotypic characterization and genome wide analysis of a

Sung-Eun Shin, Hyun Gi Koh, Nam Kyu Kang, William I Suh, Byeong-Ryool Jeong, Bongsoo Lee, Yong Keun Chang

Abstract read
In one paragraph

Article in Biotechnology for biofuels, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  5. Review
  6. Review
  7. Development and characterization of aBiotechnology for biofuels · 2020
    Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sung-Eun Shin *Department of Chemical and Biomolecular Engineering, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon, 34141 Republic of Korea.
Hyun Gi Koh *Department of Chemical and Biomolecular Engineering, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon, 34141 Republic of Korea.
Nam Kyu KangAdvanced Biomass R&D Center, 291 Daehak-ro, Yuseong-gu, Daejeon, 34141 Republic of Korea.
William I SuhAdvanced Biomass R&D Center, 291 Daehak-ro, Yuseong-gu, Daejeon, 34141 Republic of Korea.
Byeong-Ryool JeongDepartment of Chemical and Biomolecular Engineering, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon, 34141 Republic of Korea.
Bongsoo LeeDepartment of Chemical and Biomolecular Engineering, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon, 34141 Republic of Korea.ORCID 0000-0002-8841-1482
Yong Keun ChangDepartment of Chemical and Biomolecular Engineering, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon, 34141 Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMicroalgal strain development through genetic engineering has received much attention as a way to improve the traits of microalgae suitable for biofuel production. However, there are still some limitations in application of genetically modified organisms. In this regard, there has been recent interest in the isolation and characterization of superior strains naturally modified and/or adapted under a certain condition and on the interpretation of phenotypic changes through the whole genome sequencing.

resultsIn this study, we isolated and characterized a novel derivative of

conclusionOur phenotypic analysis, which emphasized lipid productivity, clearly revealed that CC-124H had a dramatically enhanced biomass and lipid content compared to the CC-124L. Moreover, SNPs and indels analysis enabled us to identify 34 of non-synonymous substitutions which may result in phenotypic changes of CC-124H. All of these results suggest that the concept of adaptive evolution combined with genome wide analysis can be applied to microalgal strain development for biofuel production.

Indexed as

Adaptive evolutionBiodieselChlamydomonas reinhardtiiFatty acid methyl esterMicroalgaeNitrogen starvation

Identifiers

PMID29296121
PMCPMC5740574

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.