Evidence map›Paper›PMID 29296074›Full record

ArticleMolecular vision2017

Loss of the cone-enriched

Aditya Venkatesh, Shun-Yun Cheng, Claudio Punzo

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Molecular vision, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.1field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Aditya VenkateshDepartment of Ophthalmology and Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA.
Shun-Yun ChengDepartment of Ophthalmology and Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA.
Claudio PunzoDepartment of Ophthalmology and Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA.
University of Massachusetts Chan Medical School · US

Funding

Delaying Cone Death in Retinitis PigmentosaR01EY023570 · NEI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI PUNZO, CLAUDIO · 2013 to 2017
$2.1M
Testing the role of Glucose deprivation during secondary cone death in Retinitis PigmentosaR21EY030166 · NEI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI PUNZO, CLAUDIO · 2019 to 2020
$461k
NEI NIH HHS R01 EY023570NEI NIH HHS R21 EY030166
6 · The paper itself

Abstract

Purpose: The apoptotic mechanisms responsible for secondary cone death in retinitis pigmentosa (RP) remain largely unknown. The cone-enriched apoptotic protease Methods: Results: Loss of Conclusions: Secondary cone death in retinitis pigmentosa is unlikely to be triggered by ER stress and is likely independent of

Indexed as

Disease Models, AnimalAnimalsApoptosisArrestinsBlotting, WesternCaspase 7Cell SurvivalElectroretinographyMiceMice, Inbred C57BLMice, KnockoutRetinaRetinal Cone Photoreceptor CellsRetinal Rod Photoreceptor CellsRetinitis Pigmentosaarrestin 1 protein, mouseArrestinsCasp7 protein, mouseCaspase 7

Identifiers

PMID29296074
PMCPMC5741377
OpenAlexW2780693901

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.