ArticleNature communications2018
Extreme haplotype variation in the desiccation-tolerant clubmoss Selaginella lepidophylla.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 1 synthesis or guideline pooled it, 133 citations in OpenAlex.
- Early "Rootprints" of Plant Terrestrialization: Selaginella Root Development Sheds Light on Root Evolution in Vascular Plants.Frontiers in plant science · 2021Pooled it
- Desiccation tolerance mechanisms in the green lineage and beyond.The New phytologist · 2026Review
- Genomics is modifying our concepts of evolution in homosporous and heterosporous vascular plants.American journal of botany · 2026Review
- Dehydration-driven organization of metabolites into NaDES-like assemblies in orthodox seeds.The New phytologist · 2026Article
- Article
- The promise of resurrection plants in enhancing crop tolerance to water scarcity.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Review
- Life on the dry side: a roadmap to understanding desiccation tolerance and accelerating translational applications.Nature communications · 2025Review
- Comparative analysis using a chromosome-scale genome assembly for Funaria hygrometrica suggests greater collinearity in mosses than in seed plants.Communications biology · 2025Article
- Gene family rearrangements and transcriptional priming drive the evolution of vegetative desiccation tolerance in Selaginella.The Plant journal : for cell and molecular biology · 2025Article
- Endophytic Bacteria from the Desiccation-Tolerant PlantMicroorganisms · 2024Article
- Article
- The Possible Earliest Allopolyploidization in Tracheophytes Revealed by Phylotranscriptomics and Morphology of Selaginellaceae.Molecular biology and evolution · 2024Article
- Convergent evolution of desiccation tolerance in grasses.Nature plants · 2024Article
- Extraordinary preservation of gene collinearity over three hundred million years revealed in homosporous lycophytes.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Utilizing transcriptomics and metabolomics to unravel key genes and metabolites of maize seedlings in response to drought stress.BMC plant biology · 2024Article
- The first homosporous lycophyte genome revealed the association between the recent dynamic accumulation of LTR-RTs and genome size variation.Plant molecular biology · 2023Article
- Combined genomic and transcriptomic analysis reveals the contribution of tandem duplication genes to low-temperature adaptation in perennial ryegrass.Frontiers in plant science · 2023Article
- Bioinformatics in Plant Breeding and Research on Disease Resistance.Plants (Basel, Switzerland) · 2022Review
- Distinct composition and amplification dynamics of transposable elements in sacred lotus (Nelumbo nucifera Gaertn.).The Plant journal : for cell and molecular biology · 2022Article
- The chromosome-level genome provides insight into the molecular mechanism underlying the tortuous-branch phenotype of Prunus mume.The New phytologist · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant genome size varies by four orders of magnitude, and most of this variation stems from dynamic changes in repetitive DNA content. Here we report the small 109 Mb genome of Selaginella lepidophylla, a clubmoss with extreme desiccation tolerance. Single-molecule sequencing enables accurate haplotype assembly of a single heterozygous S. lepidophylla plant, revealing extensive structural variation. We observe numerous haplotype-specific deletions consisting of largely repetitive and heavily methylated sequences, with enrichment in young Gypsy LTR retrotransposons. Such elements are active but rapidly deleted, suggesting "bloat and purge" to maintain a small genome size. Unlike all other land plant lineages, Selaginella has no evidence of a whole-genome duplication event in its evolutionary history, but instead shows unique tandem gene duplication patterns reflecting adaptation to extreme drying. Gene expression changes during desiccation in S. lepidophylla mirror patterns observed across angiosperm resurrection plants.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.