Evidence map›Paper›PMID 29295913›Full record

ArticlemBio2018

O-Mannosylation of Proteins Enables

Andrew L Garfoot, Kristie D Goughenour, Marcel Wüthrich, Murugesan V S Rajaram, Larry S Schlesinger, Bruce S Klein, Chad A Rappleye

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Extension ofmBio · 2022
    Article
  4. Review
  5. CoremBio · 2020
    Article
  6. Article
  7. Thermotolerance of Histoplasma capsulatum at 40 °C predominates among clinical isolates from different Latin American regions.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Andrew L GarfootDepartment of Microbiology, Ohio State University, Columbus, Ohio, USA.
Kristie D GoughenourDepartment of Microbiology, Ohio State University, Columbus, Ohio, USA.
Marcel WüthrichDepartment of Pediatrics, University of Wisconsin, Madison, Wisconsin, USA.
Murugesan V S RajaramDepartment of Microbial Infection and Immunity, Center for Microbial Interface Biology, Ohio State University, Columbus, Ohio, USA.
Larry S SchlesingerDepartment of Microbial Infection and Immunity, Center for Microbial Interface Biology, Ohio State University, Columbus, Ohio, USA.
Bruce S KleinDepartment of Pediatrics, University of Wisconsin, Madison, Wisconsin, USA.
Chad A RappleyeDepartment of Microbiology, Ohio State University, Columbus, Ohio, USA rappleye.1@osu.edu.
The Ohio State University · USInterface (United States) · USUniversity of Wisconsin–Madison · US

Funding

The Ohio State University Center for clinical and Translational ScienceUL1TR001070 · NCATS · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2013 to 2017
$22.6M
PROTECTIVE IMMUNE RESPONSES TO BLASTOMYCES DERMATITIDISR01AI040996 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI KLEIN, BRUCE STEVEN, WUETHRICH, MARCEL · 1997 to 2023
$10.4M
Molecular Pathogenesis of BlastomycosisR37AI035681 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI BRUCE Steven KLEIN · 2004 to 2026
$6.9M
Regulation of vaccine-induced anti-fungal Th17 cellsR01AI093553 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI WUETHRICH, MARCEL · 2011 to 2020
$4.5M
MOLECULAR PATHOGENESIS OF BLASTOMYCOSISR01AI035681 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI KLEIN, BRUCE STEVEN · 1995 to 2019
$3.9M
TB and Innate Immune Regulation of Lung MacrophagesR01AI059639 · NIAID · OHIO STATE UNIVERSITY · PI SCHLESINGER, LARRY S. · 2005 to 2016
$3.2M
Interdisciplinary Program in Microbe-Host BiologyT32AI112542 · NIAID · OHIO STATE UNIVERSITY · PI JUSTICE, SHERYL S, WOZNIAK, DANIEL J · 2014 to 2018
$644k
Histoplasma mannoprotein discovery and virulence role of O-linked mannosylationR21AI117122 · NIAID · OHIO STATE UNIVERSITY · PI RAPPLEYE, CHAD A · 2015 to 2016
$419k
NCATS NIH HHS UL1 TR001070NIAID NIH HHS R01 AI035681NIAID NIH HHS R01 AI040996NIAID NIH HHS R01 AI059639NIAID NIH HHS R01 AI093553NIAID NIH HHS R21 AI117122NIAID NIH HHS R37 AI035681NIAID NIH HHS T32 AI112542
6 · The paper itself

Abstract

The ability to grow at mammalian body temperatures is critical for pathogen infection of humans. For the thermally dimorphic fungal pathogen

Indexed as

Protein Processing, Post-TranslationalAnimalsDisease Models, AnimalFungal ProteinsHistoplasmaHistoplasmosisMannosyltransferasesMice, Inbred C57BLMicrobial ViabilityVirulenceFungal ProteinsMannosyltransferasesglycosylationHistoplasmamannosephagocytethermotolerance

Identifiers

PMID29295913
PMCPMC5750402
OpenAlexW2781682960

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.