Evidence map›Paper›PMID 29295591›Full record

ArticleNutrients2017

Leonurus japonicus Houtt Attenuates Nonalcoholic Fatty Liver Disease in Free Fatty Acid-Induced HepG2 Cells and Mice Fed a High-Fat Diet.

Mi-Ra Lee, Kwang Il Park, Jin Yeul Ma

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 63 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Leonurine-StandardizedJournal of microbiology and biotechnology · 2026
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Combined Extract ofFoods (Basel, Switzerland) · 2021
    Article
  15. Article
  16. Review
  17. Article
  18. Water Extract ofNutrients · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mi-Ra LeeKorea Institute of Oriental Medicine, 70 Cheomdan-Ro, Dong-Gu, Daegu 41062, Korea. withme@kiom.re.kr.
Kwang Il ParkKorea Institute of Oriental Medicine, 70 Cheomdan-Ro, Dong-Gu, Daegu 41062, Korea. kipark@kiom.re.kr.
Jin Yeul MaKorea Institute of Oriental Medicine, 70 Cheomdan-Ro, Dong-Gu, Daegu 41062, Korea. jyma@kiom.re.kr.
Korea Institute of Oriental Medicine · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the effects of a

Indexed as

Diet, High-FatLeonurusAMP-Activated Protein KinasesAnimalsBlood GlucoseCell SurvivalCytoprotectionDisease Models, AnimalDose-Response Relationship, DrugFatty Acids, NonesterifiedHepatocytesHep G2 CellsHumansInsulinInsulin ResistanceLipogenesisAMP-Activated Protein KinasesBlood GlucoseFatty Acids, NonesterifiedInsulinPlant ExtractsPPAR alphaSREBF1 protein, humanSterol Regulatory Element Binding Protein 1Triglyceridesfree fatty acidsHepG2 cellshigh-fat dietLeonurus japonicusnonalcoholic fatty liver diseaseobesity

Identifiers

PMID29295591
PMCPMC5793248
OpenAlexW2777894949

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.