Evidence map›Paper›PMID 29295572›Full record

ArticleMolecules (Basel, Switzerland)2017

Synthesis and Evaluation of Biological Activities of Aziridine Derivatives of Urea and Thiourea.

Aleksandra Kowalczyk, Adam M Pieczonka, Michał Rachwalski, Stanisław Leśniak, Paweł Stączek

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Approaches Towards Better Immunosuppressive Agents.Current topics in medicinal chemistry · 2024
    Review
  5. Article
  6. Selenium in Peptide Chemistry.Molecules (Basel, Switzerland) · 2023
    Review
  7. Article
  8. Thiosemicarbazide Derivatives Decrease the ATPase Activity ofInternational journal of molecular sciences · 2021
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aleksandra KowalczykDepartment of Microbial Genetics, Faculty of Biology and Environmental Protection, University of Lodz, Banacha 12/16, 90-237 Lodz, Poland. aleksandra.strzelczyk@biol.uni.lodz.pl.
Adam M PieczonkaDepartment of Organic and Applied Chemistry, Faculty of Chemistry, University of Lodz, Tamka 12, 91-403 Lodz, Poland. adam.pieczonka@gmail.com.
Michał RachwalskiDepartment of Organic and Applied Chemistry, Faculty of Chemistry, University of Lodz, Tamka 12, 91-403 Lodz, Poland. mrach14@wp.pl.
Stanisław LeśniakDepartment of Organic and Applied Chemistry, Faculty of Chemistry, University of Lodz, Tamka 12, 91-403 Lodz, Poland. slesniak@chemia.uni.lodz.pl.
Paweł StączekDepartment of Microbial Genetics, Faculty of Biology and Environmental Protection, University of Lodz, Banacha 12/16, 90-237 Lodz, Poland. pawel.staczek@biol.uni.lodz.pl.ORCID 0000-0003-4416-8289

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present paper, we report the synthesis and evaluation of in vitro antimicrobial activities of aziridine-thiourea derivatives. A series of aziridines in reaction with isocyanates and isothiocyanates to obtain urea and thiourea derivatives were used. The structures of all new products were confirmed based on spectroscopic data (¹H-NMR,

Indexed as

Anti-Bacterial AgentsAziridinesCell DeathEscherichia coliHeLa CellsHumansIndicators and ReagentsMicrobial Sensitivity TestsStaphylococcus aureusThioureaUreaAnti-Bacterial AgentsaziridineAziridinesIndicators and ReagentsThioureaUreaantimicrobial activityaziridinescytotoxicitythiourea derivatives

Identifiers

PMID29295572
PMCPMC5943925

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.