Evidence map›Paper›PMID 29295561›Full record

ArticleInternational journal of molecular sciences2017

Exploring the Mechanisms of Electroacupuncture-Induced Analgesia through RNA Sequencing of the Periaqueductal Gray.

Man-Li Hu, Hong-Mei Zhu, Qiu-Lin Zhang, Jing-Jing Liu, Yi Ding, Ju-Ming Zhong, Vitaly Vodyanoy, Ming-Xing Ding

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
9.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
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  8. ZnT6-mediated ZnMolecular and cellular biochemistry · 2025
    Article
  9. Article
  10. Article
  11. Effective Oriental Magic for Analgesia: Acupuncture.Evidence-based complementary and alternative medicine : eCAM · 2022
    Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Man-Li HuCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China. humanli0727@163.com.ORCID 0000-0001-8318-0454
Hong-Mei ZhuCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China. han.dong.1988@163.com.
Qiu-Lin ZhangCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China. colynqiulin@163.com.
Jing-Jing LiuCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China. Ljj779009242@163.com.
Yi DingCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China. dingyi@mail.hzau.edu.cn.
Ju-Ming ZhongCollege of Physiology and Pharmacology, Auburn University, Auburn, AL 36849, USA. zhongju@auburn.edu.
Vitaly VodyanoyCollege of Physiology and Pharmacology, Auburn University, Auburn, AL 36849, USA. vodyavi@auburn.edu.ORCID 0000-0003-3092-6245
Ming-Xing DingCollege of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China. dmx@mail.hzau.edu.cn.
Huazhong Agricultural University · CNAuburn University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electroacupuncture (EA) can relieve various pains. However, its mechanism in terms of the transcriptome is still not well-known. To explore the full profile of EA-induced molecular modification in the central nerve system, three twins of goats were selected for a match-paired experiment: EA stimulation (60 Hz, 30 min) and none-EA (control). Goats in the EA group showed an increased (

Indexed as

AnalgesiaElectroacupunctureSequence Analysis, RNAAnimalsGene Expression ProfilingGene OntologyGenomeGoatsNociceptionPeriaqueductal GrayReal-Time Polymerase Chain ReactionReproducibility of Resultselectroacupuncture analgesiagoatRNA sequencingthe periaqueductal graytranscriptome

Identifiers

PMID29295561
PMCPMC5795954
OpenAlexW2780619654

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.