Evidence map›Paper›PMID 29295234›Full record

ArticleStudies in health technology and informatics2017

Interoperability of Medication Classification Systems: Lessons Learned Mapping Established Pharmacologic Classes (EPCs) to SNOMED CT.

Scott D Nelson, Jaqui Parker, Robert Lario, Rainer Winnenburg, Mark S Erlbaum, Michael J Lincoln, Olivier Bodenreider

Abstract read
In one paragraph

Article in Studies in health technology and informatics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Problems associated with the ATC system of drug classification.Naunyn-Schmiedeberg's archives of pharmacology · 2026
    Article
  2. Article
  3. Rebuilding the Standing Prescription Renewal Orders.Applied clinical informatics · 2019
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Scott D NelsonDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.
Jaqui ParkerApelon Inc, Harford, CT, USA.
Robert LarioDepartment of Biomedical Informatics, University of Utah, Salt Lake City, UT, USA.
Rainer WinnenburgStanford Center for Biomedical Informatics Research, Stanford, CA, USA.
Mark S ErlbaumApelon Inc, Harford, CT, USA.
Michael J LincolnStanford Center for Biomedical Informatics Research, Stanford, CA, USA.
Olivier BodenreiderNational Library of Medicine, Bethesda, MD, USA.

Funding

Drug terminology at NLM - Integration, dissemination, quality assurance and applicationsZIALM010007 · NLM · NATIONAL LIBRARY OF MEDICINE · PI BODENREIDER, OLIVIER · 2016 to 2020
$3.1M
Intramural NIH HHS ZIA LM010007
6 · The paper itself

Abstract

Interoperability among medication classification systems is known to be limited. We investigated the mapping of the Established Pharmacologic Classes (EPCs) to SNOMED CT. We compared lexical and instance-based methods to an expert-reviewed reference standard to evaluate contributions of these methods. Of the 543 EPCs, 284 had an equivalent SNOMED CT class, 205 were more specific, and 54 could not be mapped. Precision, recall, and F1 score were 0.416, 0.620, and 0.498 for lexical mapping and 0.616, 0.504, and 0.554 for instance-based mapping. Each automatic method has strengths, weaknesses, and unique contributions in mapping between medication classification systems. In our experience, it was beneficial to consider the mapping provided by both automated methods for identifying potential matches, gaps, inconsistencies, and opportunities for quality improvement between classifications. However, manual review by subject matter experts is still needed to select the most relevant mappings.

Indexed as

Medication SystemsSystematized Nomenclature of MedicineHumansQuality ImprovementPharmaceutical DatabasesTopical

Identifiers

PMID29295234
PMCPMC5881380

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.