Evidence map›Paper›PMID 29294355›Full record

ReviewPharmacological research2018

Comparison of αβδ and αβγ GABA

Hua-Jun Feng, Stuart A Forman

Open access · greenAbstract readComparative StudyReview
In one paragraph

Review in Pharmacological research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

  1. The human GABAbioRxiv : the preprint server for biology · 2026
    Article
  2. Review
  3. GABADrug design, development and therapy · 2026
    Review
  4. The human GABAmicroPublication biology · 2026
    Article
  5. Article
  6. Phenols and GABAFrontiers in pharmacology · 2024
    Review
  7. Article
  8. αACS chemical neuroscience · 2022
    Article
  9. Article
  10. Direct Structural Insights into GABATrends in biochemical sciences · 2021
    Review
  11. Article
  12. αACS chemical neuroscience · 2021
    Article
  13. Article
  14. Article
  15. Synthesis of New GABAInternational journal of molecular sciences · 2019
    Article
  16. Etomidate Effects on Desensitization and Deactivation ofThe Journal of pharmacology and experimental therapeutics · 2019
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Hua-Jun FengDepartment of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, and Department of Anesthesia, Harvard Medical School, Boston, MA 02114, USA. Electronic address: feng.huajun@mgh.harvard.edu.
Stuart A FormanDepartment of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, and Department of Anesthesia, Harvard Medical School, Boston, MA 02114, USA. Electronic address: saforman@mgh.harvard.edu.
Massachusetts General Hospital · US

Funding

Synthetic Chemistry CoreP01GM058448 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI MILLER, KEITH W · 1999 to 2018
$33.6M
General Anesthetic Sites in GABA-A Receptor Subunit Interfacial PocketsR01GM089745 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI FORMAN, STUART A · 2010 to 2020
$3.8M
NIGMS NIH HHS P01 GM058448NIGMS NIH HHS R01 GM089745
6 · The paper itself

Abstract

GABA

Indexed as

Anesthetics, GeneralAnimalsBinding SitesHumansProtein SubunitsReceptors, GABA-ASynapsesAnesthetics, GeneralProtein SubunitsReceptors, GABA-AAllosteric modulationAlphaxaloneConcatemersEtomidateGABA(A) receptorsGeneral anestheticsPentobarbitalPropofolR-5-allyl-1-methyl-5-(m-trifluoromethyl-diazirynylphenyl) barbituric acid (R-mTFD-MPAB)S-1-methyl-5-propyl-5-(m-trifluoromethyl-diazirynylphenyl) barbituric acid (S-mTFD-MPPB)Tetrahydrodeoxycorticosterone (THDOC)αβγαβδ

Identifiers

PMID29294355
PMCPMC6026480
OpenAlexW2781123470

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.