ArticleAmerican journal of ophthalmology2018
Identification of Herpes Zoster-Associated Temporal Arteritis Among Cases of Giant Cell Arteritis.
Article in American journal of ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 39 citations in OpenAlex.
- Review
- Targeted RNA Sequencing of Formalin-Fixed, Paraffin-Embedded Temporal Arteries From Giant Cell Arteritis Cases Reveals Viral Signatures.Neurology(R) neuroimmunology & neuroinflammation · 2021Article
- Herpes Zoster: A Brief Definitive Review.Cornea · 2021Review
- Review
- Giant cell arteritis: Its ophthalmic manifestations.Indian journal of ophthalmology · 2021Review
- Increased Incidence of Giant Cell Arteritis After Introduction of a Live Varicella Zoster Virus Vaccine.Open forum infectious diseases · 2021Article
- No Evidence of Varicella-Zoster Virus Infection in Temporal Artery Biopsies of Anterior Ischemic Optic Neuropathy Patients With and Without Giant Cell Arteritis.The Journal of infectious diseases · 2021Article
- Is There an Association between Herpetic Infections and Giant Cell Arteritis? A Population-Based Study.Journal of clinical medicine · 2020Article
- Serious infections in people with polymyalgia rheumatica (PMR) or giant cell arteritis (GCA): a time-trend national US study.Clinical rheumatology · 2020Article
- Determinants of neurological syndromes caused by varicella zoster virus (VZV).Journal of neurovirology · 2020Review
- COVID-19 is a Real Headache!Headache · 2020Review
- The microbiome in autoimmune rheumatic disease.Best practice & research. Clinical rheumatology · 2020Review
- Could autophagy dysregulation link neurotropic viruses to Alzheimer's disease?Neural regeneration research · 2019Review
- Varicella Zoster Virus in Giant Cell Arteritis: A Review of Current Medical Literature.Neuro-ophthalmology (Aeolus Press) · 2019Review
- Clinical Features of Varicella-Zoster Virus Infection.Viruses · 2018Review
- Varicella Zoster Virus Vasculopathy.The Journal of infectious diseases · 2018Article
- Heightened risk of ischemic stroke after recent herpes zoster ophthalmicus.Journal of medical virology · 2018Article
- Cellular Stress Response to Varicella-Zoster Virus Infection of Human Skin Includes Highly Elevated Interleukin-6 Expression.Open forum infectious diseases · 2018Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
purposeTo examine whether herpes zoster antigen (also called varicella-zoster virus antigen) was detectable in temporal artery biopsies taken from individuals with giant cell arteritis (GCA).
designRetrospective comparative case series.
methodsSections of formalin-fixed paraffin-embedded temporal arteries were examined first by hematoxylin-eosin (H&E) staining to establish the diagnosis of GCA. Adjacent sections of the same biopsy were then examined by immunohistochemistry, using 2 different monoclonal antibodies against a major antigen of varicella-zoster virus called gE. Pathologic specimens were obtained from patients cared for at the University of Iowa and Washington University in St. Louis ophthalmology clinics.
resultsThe study included biopsies from 25 patients with symptoms of GCA as well as positive H&E pathology and 25 patients with symptoms compatible with GCA but negative H&E pathology. Among the GCA-positive group, 3 patients had positive staining for herpes zoster antigen. Among the GCA-negative group, herpes zoster antigen was not detected in any biopsy. In both groups of patients, false-positive staining for herpes zoster antigen was detected in the presence of calcifications in the arteries. False-positive staining was also detected on some extra-arterial skeletal muscle and erythrocytes.
conclusionHerpes zoster antigen was detected in 3 of 25 temporal arteries from patients with biopsy-proven GCA. One of the 3 positive cases was noteworthy because the patient had had herpes zoster ophthalmicus diagnosed 3 weeks before the onset of GCA symptoms. False-positive staining for herpes zoster antigen was detected on several temporal artery biopsies.
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