Evidence map›Paper›PMID 29294260›Full record

ReviewBiophysical reviews2018

Extraction and recovery processes for cynaropicrin from Cynara cardunculus L. using aqueous solutions of surface-active ionic liquids.

Emanuelle L P de Faria, Melissa V Gomes, Ana Filipa M Cláudio, Carmen S R Freire, Armando J D Silvestre, Mara G Freire

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biophysical reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Agroprospecting of Biowastes: Globe Artichoke (Molecules (Basel, Switzerland) · 2024
    Article
  3. The Employment of GeneraNutrients · 2022
    Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emanuelle L P de FariaCICECO - Aveiro Institute of Materials, Chemistry Department, University of Aveiro, University Campus of Santiago, 3810-193, Aveiro, Portugal.
Melissa V GomesCICECO - Aveiro Institute of Materials, Chemistry Department, University of Aveiro, University Campus of Santiago, 3810-193, Aveiro, Portugal.
Ana Filipa M CláudioCICECO - Aveiro Institute of Materials, Chemistry Department, University of Aveiro, University Campus of Santiago, 3810-193, Aveiro, Portugal.
Carmen S R FreireCICECO - Aveiro Institute of Materials, Chemistry Department, University of Aveiro, University Campus of Santiago, 3810-193, Aveiro, Portugal.
Armando J D SilvestreCICECO - Aveiro Institute of Materials, Chemistry Department, University of Aveiro, University Campus of Santiago, 3810-193, Aveiro, Portugal.
Mara G FreireCICECO - Aveiro Institute of Materials, Chemistry Department, University of Aveiro, University Campus of Santiago, 3810-193, Aveiro, Portugal. maragfreire@ua.pt.ORCID http://orcid.org/0000-0001-8895-0614

Funding

European Research Council 337753Fundação para a Ciência e a Tecnologia IF/01407/2012Fundação para a Ciência e a Tecnologia POCI-01-0145-FEDER-016403Fundação para a Ciência e a Tecnologia PTDC/AGR-TEC/1191/2014Fundação para a Ciência e a Tecnologia UID/CTM/50011/2013H2020 European Research Council ERC-2013-StG-337753
6 · The paper itself

Abstract

Due to the wide range of relevant biological activities and high commercial value of cynaropicrin, and aiming at developing cost-effective processes, aqueous solutions of ionic liquids (ILs) were investigated for the extraction and recovery of cynaropicrin from the leaves of Cynara cardunculus L. Both cationic (1-alkyl-3-methylimidazolium chloride) and anionic (cholinium carboxylate) surface-active ILs were investigated, as well as a wide range of conventional surfactants and molecular organic solvents, allowing us to conclude that aqueous solutions of cationic surface-active ILs display a better performance for the extraction of cynaropicrin. Operational conditions were optimized, leading to a cynaropicrin extraction yield of 3.73 wt%. The recycling of both the biomass and the solvent were further investigated to appraise the extraction media saturation and to achieve a higher cynaropicrin extraction yield (6.47 wt%). Finally, it was demonstrated that 65 wt% of the extracted cynaropicrin can be efficiently recovered by precipitation from the IL aqueous extract through the addition of water as anti-solvent, allowing us to put forward both the extraction and recovery processes of the target value-added compound from biomass followed by solvent recycling. This approach opens the door to the development of more sustainable processes using aqueous solutions of ILs instead of the volatile organic solvents commonly used in biomass processing.

Indexed as

Aqueous solutionsBiomassCynaropicrinExtractionIonic liquidsRecovery

Identifiers

PMID29294260
PMCPMC5988616

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.