Evidence map›Paper›PMID 29294258›Full record

ReviewBiophysical reviews2018

Applications of functionalized nanomaterials in photodynamic therapy.

Olayemi J Fakayode, Ncediwe Tsolekile, Sandile P Songca, Oluwatobi S Oluwafemi

Abstract readReview
In one paragraph

Review in Biophysical reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Fluorescent superparamagnetic magnetite-silica nanocomposites as carriers of a platinum diimine complex for photodynamic therapy.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025
    Article
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  14. Porphyrin as Diagnostic and Therapeutic Agent.Molecules (Basel, Switzerland) · 2019
    Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Olayemi J FakayodeDepartment of Applied Chemistry, University of Johannesburg, P.O. Box 17011, Doornfontein, Johannesburg, 2028, South Africa.
Ncediwe TsolekileDepartment of Applied Chemistry, University of Johannesburg, P.O. Box 17011, Doornfontein, Johannesburg, 2028, South Africa.
Sandile P SongcaDepartment of Chemistry, University of Zululand, PB X1001, Kwadlangezwa, 3886, South Africa.
Oluwatobi S OluwafemiDepartment of Applied Chemistry, University of Johannesburg, P.O. Box 17011, Doornfontein, Johannesburg, 2028, South Africa. Oluwafemi.oluwatobi@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Specially designed functionalized nanomaterials such as superparamagnetic iron oxide, gold, quantum dots and up- and down-conversion lanthanide series nanoparticles have consistently and completely revolutionized the biomedical environment over the past few years due to their specially inferring properties, such as specific drug delivery, plasmonic effect, optical and imaging properties, therapeutic thermal energy productionand excellent irresistible cellular penetration. These properties have been used to improve many existing disease treatment modalities and have led to the development of better therapeutic approaches for the advancement of the treatment of critical human diseases, such as cancers and related malaise. In photodynamic therapy, for example, where the delivery of therapeutic agents should ideally avoid toxicity on nearby healthy cells, superparamagnetic iron oxide nanoparticles have been shown to be capable of making photodynamic therapy (PDT) prodrugs and their associative targeting moieties tumor-specific via their unique response to an external magnetic fields. In this review, the nanomaterials commonly employed for the enhancement of photodynamic therapy are discussed. The review further describes the various methods of synthesis and characterization of these nanomaterials and highlights challenges for improving the efficacy of PDT in the future.

Indexed as

Gold nanoparticlesLanthanideNanomaterialsPhotodynamic therapyQuantum dotsSuperparamagnetic iron oxide nanoparticles

Identifiers

PMID29294258
PMCPMC5803176

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.