Evidence map›Paper›PMID 29294184›Full record

ReviewClinical autonomic research : official journal of the Clinical Autonomic Research Society2018

The physical examination as a window into autonomic disorders.

William P Cheshire, David S Goldstein

Open access · greenAbstract readReview
In one paragraph

Review in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. The grand challenge of autonomic disorders.Frontiers in neurology · 2022
    Article
  10. Review
  11. "Dysautonomia": a plea for precision.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2021
    Article
  12. Article
  13. Autonomic uprising: the tilt table test in autonomic medicine.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2019
    Review
  14. Syncope and Headache.Current pain and headache reports · 2018
    Review
  15. Catechol neurochemistry in the autonomic clinic: helpful but not absolutely required.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

William P CheshireDepartment of Neurology, Mayo Clinic, 4500 San Pablo Rd., Jacksonville, FL, 32224, USA. cheshire@mayo.edu.ORCID http://orcid.org/0000-0002-6364-5362
David S GoldsteinClinical Neurocardiology Section, Clinical Neurosciences Program, Division of Intramural Research, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, 20892, USA.
Jacksonville College · USNational Institutes of Health · US

Funding

Biomarkers of Parkinson Disease and Related DisordersZIANS003034 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI GOLDSTEIN, DAVID · 2009 to 2025
$22.8M
Mechanisms of Parkinson Disease and Related DisordersZIANS003033 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI GOLDSTEIN, DAVID · 2009 to 2022
$8.2M
Biomarkers of Parkinson Disease and Related DisordersZ01NS003034 · NINDS · NEUROLOGICAL DISORDERS AND STROKE · PI GOLDSTEIN, DAVID · 2007 to 2008
$3.9M
Treatment of Catecholaminergic NeurodegenerationZIANS003125 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI GOLDSTEIN, DAVID · 2011 to 2022
$3.2M
Mechanisms of Parkinson Disease and Related DisordersZ01NS003033 · NINDS · NEUROLOGICAL DISORDERS AND STROKE · PI GOLDSTEIN, DAVID · 2007 to 2008
$966k
Intramural NIH HHS Z01 NS003033Intramural NIH HHS Z01 NS003034Intramural NIH HHS Z99 NS999999Intramural NIH HHS ZIA NS003033Intramural NIH HHS ZIA NS003034
6 · The paper itself

Abstract

Signs of autonomic dysfunction, although at times seemingly mysterious, can contribute to diagnostic clarification and clinical investigation. Even when sophisticated autonomic testing equipment is not readily available, the experienced clinician, through educated observation and inductive reasoning-in conjunction with an intelligently obtained autonomic medical history-can discern much by a careful physical examination. Elements of the autonomic examination include variations in the pulse, postural measurements of blood pressure and heart rate, pupillary light reactions, skin coloration and temperature, patterns of sweating, and other organ-specific physical findings relevant to the individual patient's presentation. Especially important is the often neglected practice of measuring the blood pressure standing up, for orthostatic hypotension cannot be diagnosed by symptoms alone and is a common source of potential morbidity. The examination should be carried out in the context of understanding the syndromic nature of abnormalities of components of the autonomic nervous system.

Indexed as

Autonomic Nervous System DiseasesHumansNeurologic ExaminationAutonomic nervous system diseasesAutonomic pathwaysBlood pressure determinationPhysical examinationVital signs

Identifiers

PMID29294184
PMCPMC8921977
OpenAlexW2781809755

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.