Evidence map›Paper›PMID 29294156›Full record

SynthesisEuropean radiology2018

Use of the Kwak Thyroid Image Reporting and Data System (K-TIRADS) in differential diagnosis of thyroid nodules: systematic review and meta-analysis.

Bartosz Migda, Michal Migda, Marian S Migda, Rafal Z Slapa

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bartosz MigdaDiagnostic Imaging Department, Medical University of Warsaw, Kondratowicza 8, 03-242, Warsaw, Poland. bartoszmigda@gmail.ocm.
Michal MigdaClinical Unit of Obstetrics, Women's Disease and Gynaecological Oncology, United District Hospital, Collegium Medicum, University of Nicolaus Copernicus, sw. Jozefa 53-59, 87-100, Torun, Poland.
Marian S MigdaCivis-Vita Health and Medical Centre, Warszawska 20, 87-100, Torun, Poland.
Rafal Z SlapaDiagnostic Imaging Department, Medical University of Warsaw, Kondratowicza 8, 03-242, Warsaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this systematic literature review was to assess the usefulness of the Thyroid Image Reporting and Data System (K-TIRADS) classification proposed by Kwak for differentiation of thyroid nodules. MATERIAL AND

methodsFour literature databases were searched for relevant articles through early January 2017. A meta-analysis was performed to calculate pooled sensitivity, specificity, positive likelihood ratio (LR+), negative likelihood ratio (LR-) and diagnostic odds ratio (DOR). The area under the curve (AUC) from the pooled receiver operating characteristic (ROC) was used to assess the usefulness of this classification for differentiation of thyroid nodules. Meta-analysis was conducted by using meta-analysis software.

resultsWe analysed six publications describing 10,926 nodules. Pooled sensitivity, specificity, LR+, LR-, DOR, and AUC for pooled ROC were 0.983 (95 % CI 0.976-0.989), 0.552 (95 % CI 0.542-0.562), 2.666 (95 % CI 1.692-4.198), 0.05 (95 % CI 0.035-0.072), 51.020 (95 % CI 15.241-170.79) and 0.938, respectively.

conclusionsKwak TIRADS has high sensitivity and low specificity. Thus, it is very useful to discard the benign cases and to reduce the number of biopsies. KEY POINTS: • Routine, adequate standardization of thyroid nodules ultrasound classification is mandatory. • Kwak TIRADS parameters are accurate for differentiating focal thyroid lesions. • Kwak TIRADS system is simple to apply. • Kwak TIRADS system may become a useful diagnostic tool.

Indexed as

Research DesignBiopsy, Fine-NeedleDiagnosis, DifferentialHumansThyroid GlandThyroid NoduleUltrasonographyMeta-analysisRisk assessmentThyroid neoplasmThyroid nodulesUltrasonography

Identifiers

PMID29294156
PMCPMC5938289

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.