Trial reportEuropean radiology2018
Impact of noncardiac findings in patients undergoing CT coronary angiography: a substudy of the Scottish computed tomography of the heart (SCOT-HEART) trial.
Trial report in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- 2022 ACC Expert Consensus Decision Pathway on the Evaluation and Disposition of Acute Chest Pain in the Emergency Department: A Report of the American College of Cardiology Solution Set Oversight Committee.Journal of the American College of Cardiology · 2022Guideline
- Evaluating Radiation Exposure in Patients with Stable Chest Pain in the SCOT-HEART Trial.Radiology · 2023Trial
- Incidental findings on routine preoperative noncontrast chest computed tomography and chest radiography prior to cardiac surgery in the multicenter randomized controlled CRICKET study.European radiology · 2023Trial
- Detection of relevant extracardiac findings on coronary computed tomography angiography vs. invasive coronary angiography.European radiology · 2022Trial
- Concomitant screening of coronary artery disease and lung cancer with a new ultrafast-low-dose Computed Tomography protocol: A pilot randomised trial.Scientific reports · 2019Trial
- Relationship between size-specific dose estimates and image quality in coronary computed tomography angiography depending on tube voltage and scan field of view.Quantitative imaging in medicine and surgery · 2026Article
- Beyond the heart: prevalence and implications of extra-coronary findings in coronary CT angiography: a retrospective study.European radiology · 2026Article
- Clinically Relevant Extracardiac Findings at Cardiac Imaging: Insights from the European MR/CT Registry.Radiology. Cardiothoracic imaging · 2024Article
- Competence of radiologists in cardiac CT and MR imaging in Europe: insights from the ESCR Registry.European radiology · 2024Article
- High Prevalence of New Clinically Significant Findings in Patients With Embolic Stroke of Unknown Source Evaluated by Cardiac Magnetic Resonance Imaging.Journal of the American Heart Association · 2024Observational
- Article
- Incidental chest findings on coronary CT angiography: a pictorial essay and management proposal.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2022Review
- The impact of reporting magnetic resonance imaging incidental findings in the Canadian alliance for healthy hearts and minds cohort.BMC medical ethics · 2021Article
- Frequency and spectrum of incidental findings when using chest CT as a primary triage tool for COVID-19.European journal of radiology open · 2021Article
- Incidental findings on cardiac computed tomography: No new emergencies to declare!Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- SCOT-HEART trial: reshuffling our approach to stable ischemic heart disease.The British journal of radiology · 2020Article
- Conventional Computed Tomographic Calcium Scoring vs full chest CTCS for lung cancer screening: a cost-effectiveness analysis.BMC pulmonary medicine · 2020Article
- Developing a lung nodule management protocol specifically for cardiac CT: Methodology in the DISCHARGE trial.European journal of radiology open · 2020Article
- Incidental Non-cardiac Findings in Cardiovascular Imaging.Current treatment options in cardiovascular medicine · 2018Review
- Artificial Intelligence in Cardiovascular Imaging: Current Applications and New Horizons.Journal of cardiovascular echographyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
objectivesNoncardiac findings are common on coronary computed tomography angiography (CCTA). We assessed the clinical impact of noncardiac findings, and potential changes to surveillance scans with the application of new lung nodule guidelines.
methodsThis substudy of the SCOT-HEART randomized controlled trial assessed noncardiac findings identified on CCTA. Clinically significant noncardiac findings were those causing symptoms or requiring further investigation, follow-up or treatment. Lung nodule follow-up was undertaken following the 2005 Fleischner guidelines. The potential impact of the 2015 British Thoracic Society (BTS) and the 2017 Fleischner guidelines was assessed.
resultsCCTA was performed in 1,778 patients and noncardiac findings were identified in 677 (38%). In 173 patients (10%) the abnormal findings were clinically significant and in 55 patients (3%) the findings were the cause of symptoms. Follow-up imaging was recommended in 136 patients (7.6%) and additional clinic consultations were organized in 46 patients (2.6%). Malignancy was diagnosed in 7 patients (0.4%). Application of the new lung nodule guidelines would have reduced the number of patients undergoing a follow-up CT scan: 68 fewer with the 2015 BTS guidelines and 78 fewer with the 2017 Fleischner guidelines; none of these patients subsequently developed malignancy.
conclusionsClinically significant noncardiac findings are identified in 10% of patients undergoing CCTA. Application of new lung nodule guidelines will reduce the cost of surveillance, without the risk of missing malignancy. KEY POINTS: • Clinically significant noncardiac findings occur in 10% of patients undergoing CCTA. • Noncardiac findings may be an important treatable cause of chest pain • Further imaging investigations for noncardiac findings were recommended in 8% of patients after CCTA. • New lung nodule follow-up guidelines will result in cost savings.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.