Evidence map›Paper›PMID 29293466›Full record

ReviewFrontiers in bioscience (Elite edition)2018

Prostate cancer susceptibility and growth linked to Y chromosome genes.

Riddhi Patel, Ahmad O Khalifa, Ilaha Isali, Sanjeev Shukla

Abstract readReview
In one paragraph

Review in Frontiers in bioscience (Elite edition), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Repetitive DNA Sequences in the Human Y Chromosome and Male Infertility.Frontiers in cell and developmental biology · 2022
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Riddhi PatelDepartment of Urology, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH, USA.
Ahmad O KhalifaUrology Dept. Case Western Reserve University, Cleveland, Ohio and Menofia University, Shebin Al kom, Egpt.
Ilaha IsaliDepartment of Urology, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH, USA.
Sanjeev ShuklaDepartment of Urology, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH, USA, sanjeev.shukla@case.edu.

Funding

Natural Agent in Prevention of Prostate CancerR21CA190921 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI SHUKLA, SANJEEV · 2015 to 2016
$379k
NCI NIH HHS R21 CA190921
6 · The paper itself

Abstract

The role of Y chromosome in prostate cancer progression and incidence is not well known. Among the 46 chromosomes, Y chromosome determines the male gender. The Y chromosome is smaller than the X chromosome and contains only 458 genes compared to over 2000 genes found in the X chromosome. The Y chromosome is prone to high mutation rates, created exclusively in sperm cells due to the highly oxidative environment of the testis. Y chromosome harbors epigenetic information, which affects the expression of genes associated with the incidence and progression of prostate cancer. In this review, we focus on Y chromosome related genetic abnormalities, likely to be involved in the development and progression of prostate cancer.

Indexed as

Y ChromosomeAnimalsGenetic Predisposition to DiseaseHumansMaleNeoplasms, ExperimentalProstatic Neoplasms

Identifiers

PMID29293466
PMCPMC6152832

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.