Evidence map›Paper›PMID 29293155›Full record

Observational studyCritical care medicine2018

Temporal Trends in Healthcare Costs and Outcome Following ICU Admission After Traumatic Brain Injury.

Rahul Raj, Stepani Bendel, Matti Reinikainen, Sanna Hoppu, Teemu Luoto, Tero Ala-Kokko, Sami Tetri, Ruut Laitio, Timo Koivisto, Jaakko Rinne and 4 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Critical care medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Observational
  15. Article
  16. Article
  17. Article
  18. Observational
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Rahul RajDepartment of Neurosurgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Stepani BendelDepartment of Intensive Care, Kuopio University Hospital & University of Eastern Finland, Kuopio, Finland.
Matti ReinikainenDepartment of Intensive Care, North Karelia Central Hospital, Joensuu, Finland.
Sanna HoppuDepartment of Intensive Care, Tampere University Hospital & University of Tampere, Tampere, Finland.
Teemu LuotoDepartment of Neurosurgery, Tampere University Hospital & University of Tampere, Tampere, Finland.
Tero Ala-KokkoDepartment of Intensive Care, Oulu University Hospital & University of Oulu, Oulu, Finland.
Sami TetriDepartment of Neurosurgery, Oulu University Hospital & University of Oulu, Oulu, Finland.
Ruut LaitioDepartment of Intensive Care, Turku University Hospital & University of Turku, Turku, Finland.
Timo KoivistoDepartment of Neurosurgery, Kuopio University Hospital & University of Eastern Finland, Kuopio, Finland.
Jaakko RinneDepartment of Neurosurgery, Turku University Hospital & University of Turku, Turku, Finland.
Riku KivisaariDepartment of Neurosurgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Jari SiironenDepartment of Neurosurgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Alisa HigginsAustralian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Markus B SkrifvarsAustralian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess temporal trends in 1-year healthcare costs and outcome of intensive care for traumatic brain injury in Finland.

designRetrospective observational cohort study.

settingMulticenter study including four tertiary ICUs. PATIENTS: Three thousand fifty-one adult patients (≥ 18 yr) with significant traumatic brain injury treated in a tertiary ICU during 2003-2013.

interventionNone. MEASUREMENTS AND MAIN

resultsTotal 1-year healthcare costs included the index hospitalization costs, rehabilitation unit costs, and social security reimbursements. All costs are reported as 2013 U.S. dollars ($). Outcomes were 1-year mortality and permanent disability. Multivariate regression models, adjusting for case-mix, were used to assess temporal trends in costs and outcome in predefined Glasgow Coma Scale (3-8, 9-12, and 13-15) and age (18-40, 41-64, and ≥ 65 yr) subgroups. Overall 1-year survival was 76% (n = 2,304), and of 1-year survivors, 37% (n = 850) were permanently disabled. Mean unadjusted 1-year healthcare cost was $39,809 (95% CI, $38,144-$41,473) per patient. Adjusted healthcare costs decreased only in the Glasgow Coma Scale 13-15 and 65 years and older subgroups, due to lower rehabilitation costs. Adjusted 1-year mortality did not change in any subgroup (p < 0.05 for all subgroups). Adjusted risk of permanent disability decreased significantly in all subgroups (p < 0.05).

conclusionDuring the last decade, healthcare costs of ICU-admitted traumatic brain injury patients have remained largely the same in Finland. No change in mortality was noted, but the risk for permanent disability decreased significantly. Thus, our results suggest that cost-effectiveness of traumatic brain injury care has improved during the past decade in Finland.

Indexed as

Activities of Daily LivingAdolescentAdultAgedAge FactorsAPACHEBrain Injuries, TraumaticCost of IllnessCritical CareDisability EvaluationFemaleFinlandGlasgow Coma ScaleHealth ExpendituresHospital MortalityHumans

Identifiers

PMID29293155
PMCPMC5865506

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.