Evidence map›Paper›PMID 29292739›Full record

ArticleMolecules (Basel, Switzerland)2017

In Vitro Evaluation of Cytotoxicity and Permeation Study on Lysine- and Arginine-Based Lipopeptides with Proven Antimicrobial Activity.

Malgorzata Anna Dawgul, Katarzyna Ewa Greber, Sylwia Bartoszewska, Wioletta Baranska-Rybak, Wieslaw Sawicki, Wojciech Kamysz

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 37 citations in OpenAlex.

  1. Nanostructure and Collagen-Stimulating Activity of Cationic Pentapeptide Lipopeptides.Journal of peptide science : an official publication of the European Peptide Society · 2026
    Article
  2. Short Synthetic Lipopeptides CAntibiotics (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. The Short Lipopeptides (CAntibiotics (Basel, Switzerland) · 2020
    Article
  11. Double-Headed Cationic Lipopeptides: An Emerging Class of Antimicrobials.International journal of molecular sciences · 2020
    Article
  12. Article
  13. Article
  14. Ultrashort Cationic Lipopeptides-Effect ofMolecules (Basel, Switzerland) · 2020
    Article
  15. Antibacterial Activities of Lipopeptide (CInternational journal of molecular sciences · 2019
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Malgorzata Anna DawgulDepartment of Inorganic Chemistry, Faculty of Pharmacy, Medical University of Gdansk, Hallera 107, 80-416 Gdansk, Poland. mdawgul@gumed.edu.pl.
Katarzyna Ewa GreberDepartment of Physical Chemistry, Faculty of Pharmacy, Medical University of Gdansk, 80-416 Gdansk, Poland. greber@gumed.edu.pl.
Sylwia BartoszewskaDepartment of Inorganic Chemistry, Faculty of Pharmacy, Medical University of Gdansk, Hallera 107, 80-416 Gdansk, Poland. sylwiabart@gumed.edu.pl.
Wioletta Baranska-RybakDepartment of Dermatology, Faculty of Medicine, Medical University of Gdansk, 80-210 Gdansk, Poland. wiolabar@gumed.edu.pl.
Wieslaw SawickiDepartment of Physical Chemistry, Faculty of Pharmacy, Medical University of Gdansk, 80-416 Gdansk, Poland. wsawicki@gumed.edu.pl.
Wojciech KamyszDepartment of Inorganic Chemistry, Faculty of Pharmacy, Medical University of Gdansk, Hallera 107, 80-416 Gdansk, Poland. kamysz@gumed.edu.pl.
Gdańsk Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Owing to their excellent antimicrobial activities with a relatively low cost of production, lipopeptides are being intensively investigated as potential alternatives to popular antimicrobials. However, a critical obstacle for their application is a relatively high toxicity, hence a lot of attention has been paid to designing new molecules with optimal properties. In this study we synthesized the following lipopeptides: C

Indexed as

Anti-Bacterial AgentsAntifungal AgentsArginineCell LineCell SurvivalDrug DesignFungiGram-Negative BacteriaGram-Positive BacteriaHumansKeratinocytesLipopeptidesLysinePermeabilityStructure-Activity RelationshipAnti-Bacterial AgentsAntifungal AgentsArginineLipopeptidesLysineantimicrobial peptideskeratinocyteslipopeptidesskin permeationtoxicity

Identifiers

PMID29292739
PMCPMC6150024
OpenAlexW2772871590

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.