Evidence map›Paper›PMID 29292696›Full record

ArticleeLife2018

Cell-type heterogeneity in the early zebrafish olfactory epithelium is generated from progenitors within preplacodal ectoderm.

Raphaël Aguillon, Julie Batut, Arul Subramanian, Romain Madelaine, Pascale Dufourcq, Thomas F Schilling, Patrick Blader

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Raphaël AguillonCentre de Biologie du Développement (CBD, UMR5547), Centre de Biologie Intégrative (CBI, FR3743), Université de Toulouse, Toulouse, France.
Julie BatutCentre de Biologie du Développement (CBD, UMR5547), Centre de Biologie Intégrative (CBI, FR3743), Université de Toulouse, Toulouse, France.ORCID 0000-0002-1984-2094
Arul SubramanianDepartment of Developmental and Cell Biology, University of California, Irvine, United States.ORCID 0000-0001-8455-6804
Romain MadelaineCentre de Biologie du Développement (CBD, UMR5547), Centre de Biologie Intégrative (CBI, FR3743), Université de Toulouse, Toulouse, France.
Pascale DufourcqCentre de Biologie du Développement (CBD, UMR5547), Centre de Biologie Intégrative (CBI, FR3743), Université de Toulouse, Toulouse, France.
Thomas F SchillingDepartment of Developmental and Cell Biology, University of California, Irvine, United States.ORCID 0000-0003-1798-8695
Patrick BladerCentre de Biologie du Développement (CBD, UMR5547), Centre de Biologie Intégrative (CBI, FR3743), Université de Toulouse, Toulouse, France.ORCID 0000-0003-3299-6108
Université Fédérale de Toulouse Midi-Pyrénées · FRUniversity of California, Irvine · US

Funding

THE ROLE OF ATROPHIN-2 IN CARTILAGE PATTERNING AND POLARITY IN ZEBRAFISHR01DE013828 · NIDCR · UNIVERSITY OF CALIFORNIA-IRVINE · PI SCHILLING, THOMAS F · 2001 to 2025
$9.1M
Regulation of Morphogenesis and Extracellular Matrix Assembly at the Myotendinous JunctionR01AR067797 · NIAMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI Thomas F Schilling · 2016 to 2026
$3.5M
Stochastic Dynamics and Noise Control in Patterning SystemsR01GM107264 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI NIE, QING, SCHILLING, THOMAS F · 2014 to 2017
$1.3M
NIAMS NIH HHS R01 AR067797NIDCR NIH HHS R01 DE013828
6 · The paper itself

Abstract

The zebrafish olfactory epithelium comprises a variety of neuronal populations, which are thought to have distinct embryonic origins. For instance, while ciliated sensory neurons arise from preplacodal ectoderm (PPE), previous lineage tracing studies suggest that both Gonadotropin releasing hormone 3 (Gnrh3) and microvillous sensory neurons derive from cranial neural crest (CNC). We find that the expression of Islet1/2 is restricted to Gnrh3 neurons associated with the olfactory epithelium. Unexpectedly, however, we find no change in Islet1/2+ cell numbers in

Indexed as

Cell LineageAnimalsEctodermMicroscopy, ConfocalNeuronsOlfactory MucosaTime-Lapse ImagingZebrafishdevelopmental biologylineage originneuronal subtypeolfactory placodestem cellszebrafish

Identifiers

PMID29292696
PMCPMC5749950
OpenAlexW2781555778

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.