Evidence map›Paper›PMID 29292471›Full record

ReviewMedical & biological engineering & computing2018

Automated breast tumor detection and segmentation with a novel computational framework of whole ultrasound images.

Lei Liu, Kai Li, Wenjian Qin, Tiexiang Wen, Ling Li, Jia Wu, Jia Gu

Abstract readReview
In one paragraph

Review in Medical & biological engineering & computing, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Pilot study: Application of artificial intelligence for detecting left atrial enlargement on canine thoracic radiographs.Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lei LiuShenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, People's Republic of China.
Kai LiDepartment of Medical Ultrasonics, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510630, People's Republic of China.
Wenjian QinShenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, People's Republic of China.
Tiexiang WenShenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, People's Republic of China.
Ling LiShenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, People's Republic of China.
Jia WuDepartment of Radiation Oncology, Stanford University, Stanford, CA, 94305, USA. jiawu@stanford.edu.
Jia GuShenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, People's Republic of China. jia.gu@siat.ac.cn.

Funding

Quantitative Imaging Biomarkers of Treatment Response and Prognosis in Breast CancerK99CA218667 · NCI · STANFORD UNIVERSITY · PI WU, JIA · 2018 to 2019
$322k
Guangdong province science and technology plan projects 2015B020233004National Natural Science Foundation of China 61401451National Natural Science Foundation of China 61472411National Natural Science Foundation of China 61501444NCI NIH HHS K99 CA218667Shenzhen technology research project JCYJ20160429174611494Shenzhen technology research project JSGG20160429192140681
6 · The paper itself

Abstract

Due to the low contrast and ambiguous boundaries of the tumors in breast ultrasound (BUS) images, it is still a challenging task to automatically segment the breast tumors from the ultrasound. In this paper, we proposed a novel computational framework that can detect and segment breast lesions fully automatic in the whole ultrasound images. This framework includes several key components: pre-processing, contour initialization, and tumor segmentation. In the pre-processing step, we applied non-local low-rank (NLLR) filter to reduce the speckle noise. In contour initialization step, we cascaded a two-step Otsu-based adaptive thresholding (OBAT) algorithm with morphologic operations to effectively locate the tumor regions and initialize the tumor contours. Finally, given the initial tumor contours, the improved Chan-Vese model based on the ratio of exponentially weighted averages (CV-ROEWA) method was utilized. This pipeline was tested on a set of 61 breast ultrasound (BUS) images with diagnosed tumors. The experimental results in clinical ultrasound images prove the high accuracy and robustness of the proposed framework, indicating its potential applications in clinical practice. Graphical abstract ᅟ.

Indexed as

Computational BiologyImage Processing, Computer-AssistedUltrasonography, MammaryAlgorithmsBreastBreast NeoplasmsFemaleHumansModels, TheoreticalAutomatic segmentationBreastContour initializationLevel set segmentationSpeckle reductionUltrasound image

Identifiers

PMID29292471
PMCPMC6328053

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.