Evidence map›Paper›PMID 29292160›Full record

ArticleOral surgery, oral medicine, oral pathology and oral radiology2018

Assessment of alveolar bone marrow fat content using 15 T MRI.

Arthur Rodriguez Gonzalez Cortes, Ouri Cohen, Ming Zhao, Eduardo Massaharu Aoki, Rodrigo Alves Ribeiro, Lina Abu Nada, Claudio Costa, Emiko Saito Arita, Faleh Tamimi, Jerome L Ackerman

Open access · bronzeAbstract read
In one paragraph

Article in Oral surgery, oral medicine, oral pathology and oral radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Arthur Rodriguez Gonzalez CortesMartinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, USA; Department of Radiology, Harvard Medical School, Boston, Massachusetts, USA; Department of Oral Radiology, School of Dentistry, University of São Paulo, São Paulo, Brazil. Electronic address: arthuro@usp.br.
Ouri CohenMartinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, USA; Department of Radiology, Harvard Medical School, Boston, Massachusetts, USA.
Ming ZhaoMartinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, USA; Department of Radiology, Harvard Medical School, Boston, Massachusetts, USA; Department of Physics, University of Massachusetts Lowell, Lowell, Massachusetts, USA.
Eduardo Massaharu AokiDepartment of Oral Radiology, School of Dentistry, University of São Paulo, São Paulo, Brazil.
Rodrigo Alves RibeiroDepartment of Oral Implantology, School of Dentistry, Metropolitan University of Santos, Santos, Brazil.
Lina Abu NadaFaculty of Dentistry, McGill University, Montreal, Quebec, Canada.
Claudio CostaDepartment of Oral Radiology, School of Dentistry, University of São Paulo, São Paulo, Brazil.
Emiko Saito AritaDepartment of Oral Radiology, School of Dentistry, University of São Paulo, São Paulo, Brazil.
Faleh TamimiFaculty of Dentistry, McGill University, Montreal, Quebec, Canada.
Jerome L AckermanMartinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, USA; Department of Radiology, Harvard Medical School, Boston, Massachusetts, USA.
Universidade de São Paulo · BRHarvard University · USMassachusetts General Hospital · USMcGill University · CAUniversidade Metropolitana de Santos · BR

Funding

Project 4P41EB015896 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI ROSEN, BRUCE R · 2012 to 2018
$9.8M
15T ULTRAHIGH FIELD MR MICROSCOPE FOR MOUSE IMAGING: TISSUE ENGINEERINGS10RR023009 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI ACKERMAN, JEROME L · 2006 to 2006
$2.0M
NCRR NIH HHS S10 RR023009NIBIB NIH HHS P41 EB015896
6 · The paper itself

Abstract

objectivesBone marrow fat is inversely correlated with bone mineral density. The aim of this study is to present a method to quantify alveolar bone marrow fat content using a 15 T magnetic resonance imaging (MRI) scanner. STUDY

designA 15 T MRI scanner with a 13-mm inner diameter loop-gap radiofrequency coil was used to scan seven 3-mm diameter alveolar bone biopsy specimens. A 3-D gradient-echo relaxation time (T1)-weighted pulse sequence was chosen to obtain images. All images were obtained with a voxel size (58 µm

resultsMean fat tissue volume was 20.1 ± 11%. There was a significantly strong inverse correlation between fat tissue volume and BV/TV (r = -0.68; P = .045). Furthermore, there was a strong agreement between BV/TV derived from MRI and obtained with micro-CT (interclass correlation coefficient = 0.92; P = .001).

conclusionsBone marrow fat of small alveolar bone biopsy specimens can be quantified with sufficient spatial resolution using an ultra-high-field MRI scanner and a T1-weighted pulse sequence.

Indexed as

Adipose TissueAlveolar ProcessBiopsyBone DensityBone MarrowFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedX-Ray Microtomography

Identifiers

PMID29292160
PMCPMC5811345
OpenAlexW2770738309

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.