ArticleDevelopmental cognitive neuroscience2019
Processing of affective and emotionally neutral tactile stimuli in the insular cortex.
Article in Developmental cognitive neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 48 citations in OpenAlex.
- Touch, temperature, and relief: a multilevel integrative model of hedonic regulation in massage and thermal therapies.Frontiers in physiology · 2026Article
- Social approach-avoidance conflict: Behavioural, emotional, and neural correlates along a depression-social anxiety spectrum.Imaging neuroscience (Cambridge, Mass.) · 2026Article
- Can you feel it? Altered affective touch perception in a transdiagnostic sample of female adolescents with nonsuicidal self-injury.Translational psychiatry · 2025Article
- Touching Emotions: How Touch Shapes Facial Emotional Processing Among Adolescents and Young Adults.International journal of environmental research and public health · 2025Article
- Dynamic functional adaptations during touch observation in autism: connectivity strength is linked to attitudes towards social touch and social responsiveness.Molecular autism · 2025Article
- Evolutionarily conserved neural responses to affective touch in monkeys transcend consciousness and change with age.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Engrams of Fear Memory Attenuation.Advances in neurobiology · 2024Review
- Role of medial prefrontal cortex and primary somatosensory cortex in self and other-directed vicarious social touch: a TMS study.Social cognitive and affective neuroscience · 2023Article
- Social Touch: Its Mirror-like Responses and Implications in Neurological and Psychiatric Diseases.NeuroSci · 2023Review
- A psychophysical and neuroimaging analysis of genital hedonic sensation in men.Scientific reports · 2022Article
- Affective Experience and Regulation via Sleep, Touch, and "Sleep-Touch" Among Couples.Affective science · 2022Article
- The brain-body disconnect: A somatic sensory basis for trauma-related disorders.Frontiers in neuroscience · 2022Review
- Altered relationship between subjective perception and central representation of touch hedonics in adolescents with autism-spectrum disorder.Translational psychiatry · 2021Article
- Encoding of social exploration by neural ensembles in the insular cortex.PLoS biology · 2020Article
- Increased anticipatory brain response to pleasant touch in women remitted from bulimia nervosa.Translational psychiatry · 2020Article
- Psychotherapy in pain management: New viewpoints and treatment targets based on a brain theory.AIMS neuroscience · 2020Article
- The neural bases of vitality forms.National science review · 2020Review
- Tactile direction discrimination in humans after stroke.Brain communications · 2020Article
- Fascial neuromodulation: an emerging concept linking acupuncture, fasciology, osteopathy and neuroscience.European journal of translational myology · 2019Article
- Social touch: A new vista for developmental cognitive neuroscience?Developmental cognitive neuroscience · 2019Article
Corrections and comments
- Erratum issuedErratum.2020
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The insula is important for the processing of pleasant aspects of touch whereas its role in the processing of emotionally neutral touch has been less explored. Here, we used a network approach to investigate the insular processing of pleasant stroking touch and emotionally neutral vibratory touch, analysing functional magnetic resonance imaging data from 23 healthy adult participants. Vibration and skin stroking activated areas in the posterior, middle and anterior insula. Psychophysiological interaction analyses suggested that skin stroking increased functional connectivity between the posterior and ventral anterior insula. Vibration instead increased functional connectivity between the posterior and dorsal anterior insula, and induced a stronger decrease of the default mode network activity compared to stroking. These results confirmed findings from previous studies showing that the posterior insula processes affective touch information. We suggest that this is accomplished by relaying tactile information from the posterior insula to ventral anterior insula, an area tightly connected to the emotional parts of the brain. However, our results also suggested that the insula processes tactile information with less emotional valence. A central hub in this processing seemed to be the right dorsal anterior insula.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.