ReviewHearing research2018
Olivocochlear efferents: Their action, effects, measurement and uses, and the impact of the new conception of cochlear mechanical responses.
Review in Hearing research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
89 citing papers in PubMed, 178 citations in OpenAlex.
- Pain Enhances the Auditory P2 but Attenuates Mismatch Response and P3a.European journal of pain (London, England) · 2026Article
- Temporal Modulation Enhances Medial Olivocochlear Reflex Efficacy: A TEOAE Suppression Study With Amplitude-Modulated Broadband Noise.Brain and behavior · 2026Article
- Auditory contributions to postural and locomotor control: from basic research to clinical applications.Experimental brain research · 2026Review
- A computational model of the mammalian auditory periphery with a closed-loop medial olivocochlear reflex simulating across-channel efferent gain control.The Journal of the Acoustical Society of America · 2026Article
- Impaired Development of the Medial Olivocochlear System in a KCNQ4-Deficient Mouse Model.Molecular neurobiology · 2026Article
- Cochlear histopathology in macaques after noise-induced temporary threshold shifts.Hearing research · 2026Article
- A delayed pharmacological treatment strategy attenuates noise-induced tinnitus in rats.Scientific reports · 2026Article
- P2X4 receptors as the dynamic regulators of auditory sensory cell activity: a potential new mechanism for protecting hearing?Purinergic signalling · 2026Article
- Dynamic sensor adaptation based on efferent feedback for adaptive bio-inspired sound source localization.Frontiers in neuroscience · 2026Article
- On the Sharpness of Auditory Filters: Considering Subclinical Deficits Reveals Sharper Otoacoustic Emission Estimates of Frequency Selectivity in Humans.Journal of the Association for Research in Otolaryngology : JARO · 2025Article
- The Effects of Broadband Elicitor Duration on Transient-Evoked Otoacoustic Emissions and a Psychoacoustic Measure of Gain Reduction.Journal of the Association for Research in Otolaryngology : JARO · 2025Article
- Medial olivocochlear reflex dysfunction in multiple sclerosis: The influence of brainstem lesion localization and its clinical implications.World journal of clinical cases · 2025Article
- The auditory brainstem response to natural speech is not affected by selective attention.PLoS biology · 2025Article
- The Medial Olivocochlear Efferent Pathway Potentiates Cochlear Amplification in Response to Hearing Loss.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Lateral olivocochlear neurons modulate cochlear responses to noise exposure.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Modeling the impact of cochlear nerve degeneration on speech recognition performance.PloS one · 2025Article
- The auditory outcomes in non-blast related traumatic brain injury and the role of severity, aetiology and gender: a scoping review.Frontiers in neurology · 2025Review
- Resistance to age-related hearing loss in the echolocating big brown bat (Proceedings. Biological sciences · 2024Article
- Human Olivocochlear Effects: A Statistical Detection Approach Applied to the Cochlear Microphonic Evoked by Swept Tones.Journal of the Association for Research in Otolaryngology : JARO · 2024Article
- Local cochlear mechanical responses revealed through outer hair cell receptor potential measurements.Biophysical journal · 2024Article
29 more citing papers are in PubMed but not listed here.
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The anatomy and physiology of olivocochlear (OC) efferents are reviewed. To help interpret these, recent advances in cochlear mechanics are also reviewed. Lateral OC (LOC) efferents innervate primary auditory-nerve (AN) fiber dendrites. The most important LOC function may be to reduce auditory neuropathy. Medial OC (MOC) efferents innervate the outer hair cells (OHCs) and act to turn down the gain of cochlear amplification. Cochlear amplification had been thought to act only through basilar membrane (BM) motion, but recent reports show that motion near the reticular lamina (RL) is amplified more than BM motion, and that RL-motion amplification extends to several octaves below the local characteristic frequency. Data on efferent effects on AN-fiber responses, otoacoustic emissions (OAEs) and human psychophysics are reviewed and reinterpreted in the light of the new cochlear-mechanical data. The possible origin of OAEs in RL motion is considered. MOC-effect measuring methods and MOC-induced changes in human responses are also reviewed, including that ipsilateral and contralateral sound can produce MOC effects with different patterns across frequency. MOC efferents help to reduce damage due to acoustic trauma. Many, but not all, reports show that subjects with stronger contralaterally-evoked MOC effects have better ability to detect signals (e.g. speech) in noise, and that MOC effects can be modulated by attention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.