Evidence map›Paper›PMID 29291612›Full record

ArticleJournal of neurogastroenterology and motility2018

White Matter Microstructural Similarity and Diversity of Functional Constipation and Constipation-predominant Irritable Bowel Syndrome.

Jiaofen Nan, Liangliang Zhang, Qiqiang Chen, Nannan Zong, Peiyong Zhang, Xing Ji, Shaohui Ma, Yuchen Zhang, Wei Huang, Zhongzhou Du and 2 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurogastroenterology and motility, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Jiaofen NanSchool of Computer and Communication Engineering, Zhengzhou University of Light Industry, Zhengzhou, China.
Liangliang ZhangSchool of Computer and Communication Engineering, Zhengzhou University of Light Industry, Zhengzhou, China.
Qiqiang ChenSchool of Computer and Communication Engineering, Zhengzhou University of Light Industry, Zhengzhou, China.
Nannan ZongSchool of Computer and Communication Engineering, Zhengzhou University of Light Industry, Zhengzhou, China.
Peiyong ZhangFirst Affiliated Hospital of Xinxiang Medical University, Weihui, China.
Xing JiFirst Affiliated Hospital of Yan'an University, Yan'an, China.
Shaohui MaDepartment of Medical Imaging, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Yuchen ZhangDepartment of Medical Imaging, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Wei HuangSchool of Computer and Communication Engineering, Zhengzhou University of Light Industry, Zhengzhou, China.
Zhongzhou DuSchool of Computer and Communication Engineering, Zhengzhou University of Light Industry, Zhengzhou, China.
Yongquan XiaSchool of Computer and Communication Engineering, Zhengzhou University of Light Industry, Zhengzhou, China.
Ming ZhangDepartment of Medical Imaging, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Zhengzhou University of Light Industry · CNFirst Affiliated Hospital of Xi'an Jiaotong University · CNFirst Affiliated Hospital of Xinxiang Medical University · CNYan'an University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsThe Rome III criteria separated chronic constipation into functional constipation (FC) and constipation-predominant irritable bowel syndrome (IBS-C), but some researchers questioned the partitioning and treated both as distinct parts of a continuum. The study aims to explore the similarity and diversity of brain white matter between FC and IBS-C.

methodsThe voxel-wise analysis of the diffusion parameters was used to quantify the white matter changes of female brains in 18 FC patients and 20 IBS-C patients compared with a comparison group with 19 healthy controls by tract-based spatial statistics. The correlations between diffusive parameters and clinical symptoms were evaluated using a Pearson's correlation.

resultsIn comparison to healthy controls, FC patients showed a decrease of fractional anisotropy (FA) and an increase of radial diffusivity (RD) in multiple major fibers encompassing the corpus callosum (CC,

conclusionThese results may improve our understanding of the pathophysiological mechanisms underlying different types of constipation.

Indexed as

BrainDiffusion tensor imagingIrritable bowel syndrome

Identifiers

PMID29291612
PMCPMC5753909
OpenAlexW2782500486

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.