Evidence map›Paper›PMID 29291238›Full record

ArticleeNeuro

Developmental Emergence of Phenotypes in the Auditory Brainstem Nuclei of

Sarah E Rotschafer, Karina S Cramer

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Auditory processing in rodent models of autism: a systematic review.Journal of neurodevelopmental disorders · 2022
    Pooled it
  2. Pooled it
  3. Altered Auditory Maturation in Fragile X Syndrome and Its Involvement in Audiogenic Seizure Susceptibility.Autism research : official journal of the International Society for Autism Research · 2026
    Article
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  8. Hyperacusis in the AdultInternational journal of molecular sciences · 2023
    Article
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  10. Peripheral Auditory Nerve Impairment in a Mouse Model of Syndromic Autism.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  11. Article
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  13. ReducedFrontiers in cell and developmental biology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sarah E RotschaferDepartment of Neurobiology and Behavior, University of California, Irvine, CA 92697.
Karina S CramerDepartment of Neurobiology and Behavior, University of California, Irvine, CA 92697.
University of California System · US

Funding

University of California Health Participation in the National COVID Cohort Collaborative (N3C)UL1TR001414 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI COOPER, DAN M, VILAIN, ERIC J. · 2015 to 2023
$35.1M
Glial Influences on Auditory Brainstem DevelopmentR01DC010796 · NIDCD · UNIVERSITY OF CALIFORNIA-IRVINE · PI CRAMER, KARINA S · 2011 to 2020
$3.0M
NCATS NIH HHS UL1 TR001414NIDCD NIH HHS R01 DC010796
6 · The paper itself

Abstract

Fragile X syndrome (FXS), the most common monogenic cause of autism, is often associated with hypersensitivity to sound. Several studies have shown abnormalities in the auditory brainstem in FXS; however, the emergence of these auditory phenotypes during development has not been described. Here, we investigated the development of phenotypes in FXS model [

Indexed as

AnimalsAstrocytesBrain StemDisease Models, AnimalFemaleFragile X Messenger Ribonucleoprotein 1Fragile X SyndromeMaleMice, KnockoutMicrogliaPhenotypeSex CharacteristicsSynapsesFmr1 protein, mouseFragile X Messenger Ribonucleoprotein 1auditorybrainstemfragile xlateral superior olivemedial nucleus of the trapezoid bodyventral cochlear nucleus:

Identifiers

PMID29291238
PMCPMC5744645
OpenAlexW2775997847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.