Evidence map›Paper›PMID 29291226›Full record

ReviewVirusdisease2017

Role of circulatory microRNAs in the pathogenesis of hepatitis C virus.

Iqra Almas, Samia Afzal, Muhammad Idrees, Muhammad Usman Ashraf, Iram Amin, Muhammad Shahid, Khadija Zahid, Sadia Zahid

Open access · bronzeAbstract readReview
In one paragraph

Review in Virusdisease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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  5. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Iqra AlmasCentre of Excellence in Molecular Biology, University of the Punjab, Lahore, Pakistan.
Samia AfzalCentre of Excellence in Molecular Biology, University of the Punjab, Lahore, Pakistan.
Muhammad IdreesCentre of Excellence in Molecular Biology, University of the Punjab, Lahore, Pakistan.
Muhammad Usman AshrafCentre of Excellence in Molecular Biology, University of the Punjab, Lahore, Pakistan.
Iram AminCentre of Excellence in Molecular Biology, University of the Punjab, Lahore, Pakistan.
Muhammad ShahidCentre of Excellence in Molecular Biology, University of the Punjab, Lahore, Pakistan.
Khadija ZahidCentre of Excellence in Molecular Biology, University of the Punjab, Lahore, Pakistan.
Sadia ZahidCentre of Excellence in Molecular Biology, University of the Punjab, Lahore, Pakistan.
Centre of Excellence in Molecular Biology · PKUniversity of the Punjab · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis C virus (HCV) is associated with one of the major health problem in world that ultimate results in the liver cirrhosis and leads to carcinoma of hepatocellular components round the world. More than 185 million people were found to be infected with HCV. MicroRNAs are small oligonucleotide RNA having 18-22 nucleotides. Circulating mi-RNAs regulate the replication of HCV and HCV-induced liver fibrosis and HCC. By comparing the expression profiles of mi-RNAs of normal individuals with HCV infected patients, aberrant changes in expression of different mi-RNAs have been observed so it can be predicted that these mi-RNAs are associated with and play a central role in the hepatitis C infection and diseases associated with it. This review demonstrates the major role of circulatory microRNAs in the HCV and HCV associated ailments.

Indexed as

HCCHCVMiRNAPathogenecity

Identifiers

PMID29291226
PMCPMC5747848
OpenAlexW2769864680

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.