Evidence map›Paper›PMID 29291140›Full record

ArticleJournal of stem cell research & therapy2017

Mesenchymal Stem Cell Soluble Mediators and Cystic Fibrosis.

Morgan T Sutton, David Fletcher, Nicole Episalla, Lauren Auster, Sukhmani Kaur, Mary Chandler Gwin, Michael Folz, Dante Velasquez, Varun Roy, Rolf van Heeckeren and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of stem cell research & therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Utilization of Stem Cells in Medicine: A Narrative Review.International journal of molecular sciences · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Enhancing Cystic Fibrosis Immune Regulation.Frontiers in pharmacology · 2021
    Article
  17. Cell-Based Therapeutic Approaches for Cystic Fibrosis.International journal of molecular sciences · 2020
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Morgan T SuttonDepartment of Pediatrics, Case Western Reserve University, Cleveland Ohio 44106-4948.
David FletcherDepartment of Pediatrics, Case Western Reserve University, Cleveland Ohio 44106-4948.
Nicole EpisallaDepartment of Pediatrics, Case Western Reserve University, Cleveland Ohio 44106-4948.
Lauren AusterDepartment of Pediatrics, Case Western Reserve University, Cleveland Ohio 44106-4948.
Sukhmani KaurDepartment of Pediatrics, Case Western Reserve University, Cleveland Ohio 44106-4948.
Mary Chandler GwinDepartment of Pediatrics, Case Western Reserve University, Cleveland Ohio 44106-4948.
Michael FolzSchool of Engineering, Case Western Reserve University, Cleveland Ohio 44106-4948.
Dante VelasquezDepartment of Pediatrics, Case Western Reserve University, Cleveland Ohio 44106-4948.
Varun RoyDepartment of Pediatrics, Case Western Reserve University, Cleveland Ohio 44106-4948.
Rolf van HeeckerenDepartment of Pediatrics, Case Western Reserve University, Cleveland Ohio 44106-4948.
Donald P LennonDepartment of Biology, Case Western Reserve University, Cleveland Ohio 44106-4948.
Arnold I CaplanDepartment of Biology, Case Western Reserve University, Cleveland Ohio 44106-4948.
Tracey L BonfieldDepartment of Pediatrics, Case Western Reserve University, Cleveland Ohio 44106-4948.
Case Western Reserve University · US

Funding

Cell Based Therapies for Cystic FibrosisR21HL104362 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI BONFIELD, TRACEY L · 2011 to 2012
$432k
NHLBI NIH HHS R21 HL104362
6 · The paper itself

Abstract

Human Mesenchymal stem cells (hMSCs) secrete products (supernatants) that are anti-inflammatory and antimicrobial. We have previously shown that hMSCs decrease inflammation and

Indexed as

Anti-InflammationAnti-Inflammatory CytokinesChemokineschemotaxiscystic fibrosisCytokinesMesenchymal stem cellsPPARγ

Identifiers

PMID29291140
PMCPMC5747256
OpenAlexW2762500066

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.