Evidence map›Paper›PMID 29290989›Full record

ArticleOncotarget2017

Upregulation of miR-126-3p promotes human saphenous vein endothelial cell proliferation

Qingxi Qu, Weidong Bing, Xiangbin Meng, Jie Xi, Xiao Bai, Qing Liu, Yaqiu Guo, Xin Zhao, Yanwen Bi

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Qingxi QuDepartment of Cardiovascular Surgery, Qilu Hospital of Shandong University, Jinan, Shandong 250012, China.
Weidong BingDepartment of Cardiovascular Surgery, Qilu Hospital of Shandong University, Jinan, Shandong 250012, China.
Xiangbin MengDepartment of Cardiovascular Surgery, Qilu Hospital of Shandong University, Jinan, Shandong 250012, China.
Jie XiDepartment of Cardiovascular Surgery, Qilu Hospital of Shandong University, Jinan, Shandong 250012, China.
Xiao BaiDepartment of Cardiovascular Surgery, Qilu Hospital of Shandong University, Jinan, Shandong 250012, China.
Qing LiuDepartment of Ultrasound, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250012, China.
Yaqiu GuoDepartment of Anesthesiology, Jinan Maternity and Child Health Care Hospital, Jinan, Shandong 250012, China.
Xin ZhaoDepartment of Cardiovascular Surgery, Qilu Hospital of Shandong University, Jinan, Shandong 250012, China.
Yanwen BiDepartment of Cardiovascular Surgery, Qilu Hospital of Shandong University, Jinan, Shandong 250012, China.
Qilu Hospital of Shandong University · CNJinan Maternity And Care Hospital · CNShandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Poor long-term patency of vein grafts remains an obstacle in coronary artery bypass grafting (CABG) surgery using an autologous saphenous vein graft. Recent studies have revealed that miR-126-3p promotes vascular integrity and angiogenesis. We aimed to identify the role of miR-126-3p in the setting of vein graft disease and investigate the value of miR-126-3p agomir as a future gene therapy in vein graft failure. Expression analysis of circulating miR-126-3p in plasma from CABG patients established the basic clues that miR-126-3p participates in CABG. The

Indexed as

endothelial cellshuman saphenous veinmiRNAsneointimal formationvein graft

Identifiers

PMID29290989
PMCPMC5739774
OpenAlexW2767769087

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.