Evidence map›Paper›PMID 29290953›Full record

ArticleOncotarget2017

Viral

Karin Hoppe-Seyler, Anja Honegger, Felicitas Bossler, Jasmin Sponagel, Julia Bulkescher, Claudia Lohrey, Felix Hoppe-Seyler

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 25 citations in OpenAlex.

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  19. Regulation of Cellular Metabolism by High-Risk Human Papillomaviruses.International journal of molecular sciences · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Karin Hoppe-SeylerMolecular Therapy of Virus-Associated Cancers (F065), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Anja HoneggerMolecular Therapy of Virus-Associated Cancers (F065), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Felicitas BosslerMolecular Therapy of Virus-Associated Cancers (F065), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Jasmin SponagelMolecular Therapy of Virus-Associated Cancers (F065), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Julia BulkescherMolecular Therapy of Virus-Associated Cancers (F065), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Claudia LohreyMolecular Therapy of Virus-Associated Cancers (F065), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Felix Hoppe-SeylerMolecular Therapy of Virus-Associated Cancers (F065), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
German Cancer Research Center · DEHeidelberg University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oncogenic types of human papillomaviruses (HPVs) are major human carcinogens. Cancer cells typically exhibit metabolic alterations which support their malignant growth. These include an enhanced rate of aerobic glycolysis ('Warburg effect') which in cancer cells is often linked to an increased expression of the rate-limiting glycolytic enzyme Hexokinase 2 (HK2). Intriguingly, recent studies indicate that the HPV

Indexed as

cervical cancerhexokinase 2human papillomavirus

Identifiers

PMID29290953
PMCPMC5739738
OpenAlexW2769423083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.