Evidence map›Paper›PMID 29290840›Full record

ArticleThe open dentistry journal2017

Correlation Between Metabolic Syndrome, Periodontitis and Reactive Oxygen Species Production. A Pilot Study.

Romeo Patini, Patrizia Gallenzi, Gianrico Spagnuolo, Massimo Cordaro, Monica Cantiani, Adriana Amalfitano, Alessandro Arcovito, Cinzia Callà, Gertrude Mingrone, Giuseppina Nocca

Open access · hybridAbstract read
In one paragraph

Article in The open dentistry journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

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  15. Biological and Chemo-Physical Features of Denture Resins.Materials (Basel, Switzerland) · 2020
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  17. Spine and TMJ: A Pathophysiology Report.Journal of functional morphology and kinesiology · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Romeo PatiniInstitute of Dentistry, Università Cattolica del Sacro Cuore, Largo Francesco Vito - 00168 Rome , Italy.
Patrizia GallenziInstitute of Dentistry, Università Cattolica del Sacro Cuore, Largo Francesco Vito - 00168 Rome , Italy.
Gianrico SpagnuoloDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, Università di Napoli Federico II, via S. Pansini, 5-80131 Naples, Italy.
Massimo CordaroInstitute of Dentistry, Università Cattolica del Sacro Cuore, Largo Francesco Vito - 00168 Rome , Italy.
Monica CantianiInstitute of Dentistry, Università Cattolica del Sacro Cuore, Largo Francesco Vito - 00168 Rome , Italy.
Adriana AmalfitanoInstitute of Biochemistry and Clinical Biochemistry, Università Cattolica del Sacro Cuore, Largo Francesco Vito - 00168 Rome , Italy.
Alessandro ArcovitoInstitute of Biochemistry and Clinical Biochemistry, Università Cattolica del Sacro Cuore, Largo Francesco Vito - 00168 Rome , Italy.
Cinzia CallàInstitute of Biochemistry and Clinical Biochemistry, Università Cattolica del Sacro Cuore, Largo Francesco Vito - 00168 Rome , Italy.
Gertrude MingroneDepartment of Internal Medicine, Università Cattolica del Sacro Cuore, Largo Francesco Vito - 00168 Rome , Italy.
Giuseppina NoccaInstitute of Biochemistry and Clinical Biochemistry, Università Cattolica del Sacro Cuore, Largo Francesco Vito - 00168 Rome , Italy.
Università Cattolica del Sacro Cuore · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveMetabolic syndrome (MetS) is associated with an increased risk of periodontitis even if the mechanism is unknown. Since both MetS and periodontitis are characterized by an alteration of inflammation status, the aim of this pilot study was to determine if differences in ROS metabolism of phagocytes isolated from (A) patients with MetS, (B) patients with both MetS and mild periodontitis, (C) healthy subjects and (D) normal weight subjects with mild periodontitis, were present.

methodsROS metabolism was studied by a Chemiluminescence (CL) technique: the system was made up of luminol (100 nmol/L) and cells (1 × 10 STATISTICAL ANALYSIS: All results are mean ± standard deviation (SD). The group of means was compared by the analysis of variance "(ANOVA)". A value of

resultsResults showed that basal ROS production (both from PMNs and from PBMs) of groups A, B and D was increased with respect to that obtained from group C (

conclusionThese results are congruent with literature data, although the actual clinical relevance of the phenomenon remains to be evaluated.

Indexed as

ChemiluminescenceLeukocytesMetabolic syndromeObesityPeriodontitisROS metabolism

Identifiers

PMID29290840
PMCPMC5738754
OpenAlexW2768536892

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.