Evidence map›Paper›PMID 29290822›Full record

ArticleTheranostics2018

MiR-31-5p-ACOX1 Axis Enhances Tumorigenic Fitness in Oral Squamous Cell Carcinoma Via the Promigratory Prostaglandin E2.

Yi-Hsuan Lai, Hsuan Liu, Wei-Fan Chiang, Ting-Wen Chen, Lichieh Julie Chu, Jau-Song Yu, Shu-Jen Chen, Hua-Chien Chen, Bertrand Chin-Ming Tan

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 108 citations in OpenAlex.

  1. Article
  2. Frontiers in medicine · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. MicroRNA-31 induced byiScience · 2023
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yi-Hsuan LaiGraduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Guishan, Taoyuan, Taiwan, ROC.
Hsuan LiuGraduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Guishan, Taoyuan, Taiwan, ROC.
Wei-Fan ChiangDepartment of Oral & Maxillofacial Surgery, Chi-Mei Medical Center, Liouying, Tainan, Taiwan, ROC.
Ting-Wen ChenMolecular Medicine Research Center, Chang Gung University, Guishan, Taoyuan, Taiwan, ROC.
Lichieh Julie ChuMolecular Medicine Research Center, Chang Gung University, Guishan, Taoyuan, Taiwan, ROC.
Jau-Song YuGraduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Guishan, Taoyuan, Taiwan, ROC.
Shu-Jen ChenACT Genomics, Co., Ltd., Neihu, Taipei, Taiwan, ROC.
Hua-Chien ChenACT Genomics, Co., Ltd., Neihu, Taipei, Taiwan, ROC.
Bertrand Chin-Ming TanGraduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Guishan, Taoyuan, Taiwan, ROC.
Chang Gung University · TWGenomics Research Center, Academia Sinica · TWNational Yang Ming Chiao Tung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During neoplastic development, a multitude of changes in genome-encoded information are progressively selected to confer growth and survival advantages to tumor cells. microRNAs-mRNAs regulatory networks, given their role as a critical layer of robust gene expression control, are frequently altered in neoplasm. However, whether and how these gene perturbations impact metabolic homeostasis remains largely unresolved.

Indexed as

Acyl-CoA OxidaseBiomarkers, TumorCarcinogenesisCarcinoma, Squamous CellCell Line, TumorCell MovementCell ProliferationDinoprostoneGene Expression Regulation, NeoplasticHumansMicroRNAsMouth NeoplasmsSignal TransductionUp-RegulationAcyl-CoA OxidaseBiomarkers, TumorDinoprostoneMicroRNAsMIRN31 microRNA, humanACOX1lipid metabolismmiRNA-mRNA networkoral squamous cell carcinomaprostaglandins

Identifiers

PMID29290822
PMCPMC5743562
OpenAlexW2770134339

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.