Evidence map›Paper›PMID 29290807›Full record

ArticleTheranostics2018

Tiresias: Context-sensitive Approach to Decipher the Presence and Strength of MicroRNA Regulatory Interactions.

Jinkyu Koo, Jinyi Zhang, Somali Chaterji

Abstract read
In one paragraph

Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Performance and efficiency of machine learning algorithms for analyzing rectangular biomedical data.Laboratory investigation; a journal of technical methods and pathology · 2021
    Article
  5. Machine learning analysis of TCGA cancer data.PeerJ. Computer science · 2021
    Article
  6. Review
  7. Theranostic application ofTheranostics · 2020
    Article
  8. Article
  9. Non-Coding RNAs and their Integrated Networks.Journal of integrative bioinformatics · 2019
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jinkyu KooElectrical and Computer Engineering, Purdue University, West Lafayette, IN, USA.
Jinyi ZhangComputer Science, Columbia University, New York, NY, USA.
Somali ChaterjiComputer Science, Purdue University, West Lafayette, IN, USA.

Funding

Continued Development and Maintenance of the MG-RAST Metagenomics PipelineR01AI123037 · NIAID · PURDUE UNIVERSITY · PI GRAMA, ANANTH, MEYER, FOLKER · 2016 to 2020
$3.7M
Theoretical Foundations and Software Infrastructure for Biological Network DatabasesU01CA198941 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI KOYUTURK, MEHMET · 2015 to 2017
$1.4M
NCI NIH HHS U01 CA198941NIAID NIH HHS R01 AI123037
6 · The paper itself

Abstract

MicroRNAs (miRNAs) are short non-coding RNAs that regulate expression of target messenger RNAs (mRNAs) post-transcriptionally. Understanding the precise regulatory role of miRNAs is of great interest since miRNAs have been shown to play an important role in development, diseases, and other biological processes. Early work on miRNA target prediction has focused on static sequence-driven miRNA-mRNA complementarity. However, recent research also utilizes expression-level data to study context-dependent regulation effects in a more dynamic, physiologically-relevant setting.

Indexed as

Neural Networks, ComputerAnimalsBayes TheoremComputational BiologyGene Expression Regulation, NeoplasticHumansMachine LearningMicroRNAsRNA, MessengerMicroRNAsRNA, Messengerartificial neural networksBayesian optimizationbreast cancercondition-specific regulation.machine learningmessenger RNAMicroRNA

Identifiers

PMID29290807
PMCPMC5743474

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.