Evidence map›Paper›PMID 29290804›Full record

ArticleTheranostics2018

An Albumin-binding Polypeptide Both Targets Cytotoxic T Lymphocyte Vaccines to Lymph Nodes and Boosts Vaccine Presentation by Dendritic Cells.

Peng Wang, Peng Zhao, Shuyun Dong, Tiefeng Xu, Xiao He, Mingnan Chen

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Vaccine delivery systems toward lymph nodes.Advanced drug delivery reviews · 2021
    Review
  6. Review
  7. Article
  8. Article
  9. Promotion of CTL epitope presentation by a nanoparticle with environment-responsive stability and phagolysosomal escape capacity.Journal of controlled release : official journal of the Controlled Release Society · 2020
    Article
  10. Nanoparticle cancer vaccines: Design considerations and recent advances.Asian journal of pharmaceutical sciences · 2020
    Review
  11. Implantable and Injectable Biomaterial Scaffolds for Cancer Immunotherapy.Frontiers in bioengineering and biotechnology · 2020
    Review
  12. Engineering patient-specific cancer immunotherapies.Nature biomedical engineering · 2019
    Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Peng WangDepartment of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, Salt Lake City, UT 84112, USA.
Peng ZhaoDepartment of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, Salt Lake City, UT 84112, USA.
Shuyun DongDepartment of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, Salt Lake City, UT 84112, USA.
Tiefeng XuThe First Affiliated Hospital and The Oncological Institute, Hainan Medical University, Haikou City, Hainan Province 570102, China.
Xiao HeDepartment of Pathology, University of Utah, Salt Lake City, UT 84112, USA.
Mingnan ChenDepartment of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, Salt Lake City, UT 84112, USA.
University of Utah · USHainan Medical University · CN

Funding

Inhibition of metastasis-initiating cells by chimeric polypeptide nanoparticlesR00CA153929 · NCI · UNIVERSITY OF UTAH · PI CHEN, MINGNAN · 2012 to 2014
$721k
Enhancing cytotoxic T lymphocyte (CTL) responses by directly loading CTL epitope vaccines onto MHC Class I complexes on the dendritic cell surfaceR21EB024083 · NIBIB · UNIVERSITY OF UTAH · PI CHEN, MINGNAN · 2017 to 2018
$417k
NCI NIH HHS R00 CA153929NIBIB NIH HHS R21 EB024083
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCell LineChromatography, GelDendritic CellsEndosomesFemaleLymph NodesLymphocyte ActivationLysosomesMiceMice, Inbred C57BLMicroscopy, FluorescencePeptidesSurface Plasmon ResonanceT-Lymphocytes, CytotoxicVaccinesPeptidesVaccinesAlbumin-binding domainAntigen presentationCytosolic accumulation.Cytotoxic T lymphocyte responseLymph node targeting

Identifiers

PMID29290804
PMCPMC5743471
OpenAlexW2768218098

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.