ArticleWorld journal of gastroenterology2017
Efficacy of noninvasive evaluations in monitoring inflammatory bowel disease activity: A prospective study in China.
Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 44 citations in OpenAlex.
- Correlation between inflammatory markers and disease severity in ulcerative colitis.World journal of gastrointestinal surgery · 2025Article
- Comparative study of fecal calprotectin levels in ulcerative colitis versus irritable bowel syndrome.Bioinformation · 2025Article
- The relationship between Glasgow Prognostic Score and hospital duration in patients with inflammatory bowel diseases.Asia Pacific journal of clinical nutrition · 2024Article
- Utility of four machine learning approaches for identifying ulcerative colitis and Crohn's disease.Heliyon · 2024Article
- Treat to target in Crohn's disease: A practical guide for clinicians.World journal of gastroenterology · 2024Review
- New score models for assessing disease activity in Crohn's disease based on bowel ultrasound and biomarkers: Ideal surrogates for endoscopy or imaging.Clinical and translational science · 2023Article
- Review
- Peripheral blood T-lymphocyte subsets are potential biomarkers of disease severity and clinical outcomes in patients with ulcerative colitis: a retrospective study.BMC gastroenterology · 2023Article
- An Improved Score for the Evaluation of Mucosal Healing in Inflammatory Bowel Disease-A Pilot Study.Journal of clinical medicine · 2023Article
- The treatment principles and targets for intestinal Behcet's disease.Therapeutic advances in gastroenterology · 2023Review
- Predictive value of faecal calprotectin in ulcerative colitis - single centre experience.Annals of medicine · 2022Article
- Evaluation of Fecal Calprotectin, Serum C-Reactive Protein, Erythrocyte Sedimentation Rate, Seromucoid and Procalcitonin in the Diagnostics and Monitoring of Crohn's Disease in Children.Journal of clinical medicine · 2022Article
- Faecal Calprotectin in Assessment of Mucosal Healing in Adults with Inflammatory Bowel Disease: A Meta-Analysis.Journal of clinical medicine · 2021Review
- Effective immune-inflammation index for ulcerative colitis and activity assessments.World journal of clinical cases · 2021Article
- Article
- The New Proactive Approach and Precision Medicine in Crohn's Disease.Biomedicines · 2020Review
- Biochemical Biomarkers of Mucosal Healing for Inflammatory Bowel Disease in Adults.Diagnostics (Basel, Switzerland) · 2020Review
- Incorporating Fecal Calprotectin Into Clinical Practice for Patients With Moderate-to-Severely Active Ulcerative Colitis Treated With Biologics or Small-Molecule Inhibitors.The American journal of gastroenterology · 2020Article
- The association among enterobacterial flora, dietary factors, and prognosis in patients with ulcerative colitis.Journal of clinical biochemistry and nutrition · 2020Article
- Unmet Medical Needs in the Management of Ulcerative Colitis: Results of an Italian Delphi Consensus.Gastroenterology research and practice · 2019Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo optimize the efficacy of noninvasive evaluations in monitoring the endoscopic activity of inflammatory bowel disease (IBD).
methodsFecal calprotectin (FC), clinical activity index (CDAI or CAI), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and procalcitonin (PCT) were measured for 136 IBD patients. Also, FC was measured in 25 irritable bowel syndrome (IBS) patients that served as controls. Then, endoscopic activity was determined by other two endoscopists for colonic or ileo-colonic Crohn's disease (CICD) with the "simple endoscopic score for Crohn's disease" (SES-CD), CD-related surgery patients with the Rutgeerts score, and ulcerative colitis (UC) with the Mayo score. The efficacies of these evaluations to predict the endoscopic disease activity were assessed by Mann-Whitney test, χ
resultsThe median FC levels in CD, UC, and IBS patients were 449.6 (IQR, 137.9-1344.8), 497.9 (IQR, 131.7-118.0), and 9.9 (IQR, 049.7) μg/g, respectively (P < 0.001). For FC, CDAI or CAI, CRP, and ESR differed significantly between endoscopic active and remission in CICD and UC patients, but not in CD-related surgery patients. The SES-CD correlated closely with levels of FC (
conclusionFC is the most promising noninvasive evaluation for monitoring the endoscopic activity of CICD and UC. CFA might be more accurate for IBD activity evaluation.
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