Evidence map›Paper›PMID 29290056›Full record

ArticleJournal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology2018

Presynaptic serotonin 5-HT

N I Kalinina, Aleksey V Zaitsev, N P Vesselkin

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Serotonin Modulates Differently the Functional Properties of Damaged and Intact Motoneurons in the Frog Spinal Cord.Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

N I KalininaSechenov Institute of Evolutionary Physiology and Biochemistry of the Russian Academy of Sciences (IEPhB), prospekt Toreza 44, Saint Petersburg, 194223, Russia.
Aleksey V ZaitsevSechenov Institute of Evolutionary Physiology and Biochemistry of the Russian Academy of Sciences (IEPhB), prospekt Toreza 44, Saint Petersburg, 194223, Russia. aleksey_zaitsev@mail.ru.ORCID 0000-0002-4503-0647
N P VesselkinSechenov Institute of Evolutionary Physiology and Biochemistry of the Russian Academy of Sciences (IEPhB), prospekt Toreza 44, Saint Petersburg, 194223, Russia.
Institute of Evolutionary Physiology and Biochemistry · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endogenous monoamine 5-hydroxytryptamine (5-HT, serotonin) is a phylogenetically ancient neurotransmitter present in vertebrates. The functions of 5-HT in central nervous system are intensively studied; however, the presynaptic effects of 5-HT in frog spinal motoneurons are practically unexplored. We have previously shown that 5-HT decreases the frequency of glycinergic miniature inhibitory postsynaptic potentials (mIPSPs), but does not affect the frequency of GABAergic mIPSPs and increases the frequency of glutamatergic postsynaptic potentials. In the present study, using pharmacological methods and intracellular recordings in motoneurons from an adult frog's isolated spinal cord, we aimed to identify the 5-HT receptor subtype responsible for inhibiting the release of glycine. Аn agonist of 5-HT

Indexed as

8-Hydroxy-2-(di-n-propylamino)tetralinAnimalsGlycineMethysergideMiniature Postsynaptic PotentialsMotor NeuronsNeural InhibitionPresynaptic TerminalsRana ridibundaReceptors, SerotoninReceptors, Serotonin, 5-HT1Receptors, Serotonin, 5-HT2SerotoninSerotonin AgentsSpinal CordTissue Culture Techniques8-Hydroxy-2-(di-n-propylamino)tetralinGlycineMethysergideReceptors, SerotoninReceptors, Serotonin, 5-HT1Receptors, Serotonin, 5-HT2Serotoninserotonin 7 receptorSerotonin Agents5-HT1B/D receptorsInhibitory postsynaptic potentialMotoneuronRana ridibundaSpinal cord

Identifiers

PMID29290056
OpenAlexW2777784415

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.