Evidence map›Paper›PMID 29290034›Full record

ArticleJournal of pharmacokinetics and pharmacodynamics2018

Pharmacokinetics of dexmedetomidine during analgosedation in ICU patients.

Piotr Smuszkiewicz, Paweł Wiczling, Justyna Ber, Justyna Warzybok, Tomasz Małkiewicz, Jan Matysiak, Agnieszka Klupczyńska, Iwona Trojanowska, Zenon Kokot, Edmund Grześkowiak and 2 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of pharmacokinetics and pharmacodynamics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Piotr SmuszkiewiczDepartment of Anesthesiology, Intensive Therapy and Pain Treatment, Clinical Hospital, Poznan University of Medical Sciences, Przybyszewskiego 49 Street, 60-780, Poznań, Poland.
Paweł WiczlingDepartment of Biopharmacy and Pharmacodynamics, Medical University of Gdańsk, Hallera 107 Street, 80-416, Gdańsk, Poland.
Justyna BerDepartment of Clinical Pharmacy and Biopharmacy, Poznan University of Medical Sciences, Św. Marii Magdaleny 14 Street, 61-861, Poznań, Poland.
Justyna WarzybokDepartment of Clinical Pharmacy and Biopharmacy, Poznan University of Medical Sciences, Św. Marii Magdaleny 14 Street, 61-861, Poznań, Poland.
Tomasz MałkiewiczDepartment of Teaching Anesthesiology and Intensive Therapy, Poznan University of Medical Sciences, Św. Marii Magdaleny 14 Street, 61-861, Poznań, Poland.
Jan MatysiakDepartment of Inorganic and Analytical Chemistry, Poznan University of Medical Sciences, Grunwaldzka 6 Street, 60-780, Poznań, Poland.
Agnieszka KlupczyńskaDepartment of Inorganic and Analytical Chemistry, Poznan University of Medical Sciences, Grunwaldzka 6 Street, 60-780, Poznań, Poland.
Iwona TrojanowskaDepartment of Anesthesiology, Intensive Therapy and Pain Treatment, Clinical Hospital, Poznan University of Medical Sciences, Przybyszewskiego 49 Street, 60-780, Poznań, Poland.
Zenon KokotDepartment of Inorganic and Analytical Chemistry, Poznan University of Medical Sciences, Grunwaldzka 6 Street, 60-780, Poznań, Poland.
Edmund GrześkowiakDepartment of Clinical Pharmacy and Biopharmacy, Poznan University of Medical Sciences, Św. Marii Magdaleny 14 Street, 61-861, Poznań, Poland.
Wojciech KrzyzanskiDepartment of Pharmaceutical Sciences, University at Buffalo, 370 Kapoor Hall, Buffalo, NY, 14214, USA.
Agnieszka BienertDepartment of Clinical Pharmacy and Biopharmacy, Poznan University of Medical Sciences, Św. Marii Magdaleny 14 Street, 61-861, Poznań, Poland. agnbienert@op.pl.
Poznan University of Medical Sciences · PLGdańsk Medical University · PLUniversity at Buffalo, State University of New York · US

Funding

Polish National Science Centre 2015/17/B/NZ7/03032
6 · The paper itself

Abstract

Dexmedetomidine (DEX) is a fairly new alfa

Indexed as

AdultAgedAged, 80 and overDexmedetomidineFemaleHumansHypnotics and SedativesInfusions, IntravenousIntensive Care UnitsMaleMetabolic Clearance RateMiddle AgedModels, BiologicalNonlinear DynamicsYoung AdultDexmedetomidineHypnotics and SedativesDexmedetomidineICUPharmacokineticSedation

Identifiers

PMID29290034
PMCPMC5845053
OpenAlexW2777486295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.