Evidence map›Paper›PMID 29289938›Full record

ArticleBMJ open2017

Pharmacological interventions for preventing post-operative atrial fibrillation in patients undergoing cardiac surgery: a network meta-analysis protocol.

Xiaoqin Wang, Liang Yao, Long Ge, Lun Li, Fuxiang Liang, Qi Zhou, Yaolong Chen, Yongfeng Wang, Kehu Yang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Xiaoqin WangEvidence Based Medicine Centre, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
Liang YaoClinical Research and Evidence Based Medicine Institute of the People's Hospital of Gansu Province, Lanzhou, Gansu, China.
Long GeEvidence Based Medicine Centre, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
Lun LiXiangya Hospital of Central South University, Lanzhou, China.
Fuxiang LiangThe First Hospital of Lanzhou University, Lanzhou, China.
Qi ZhouThe First Hospital of Lanzhou University, Lanzhou, China.
Yaolong ChenEvidence Based Medicine Centre, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
Yongfeng WangGansu University of Chinese Medicine, Lanzhou, China.
Kehu YangEvidence Based Medicine Centre, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
Lanzhou University · CNGansu Provincial Hospital · CNGansu University of Traditional Chinese Medicine · CNXiangya Hospital Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPostoperative atrial fibrillation (POAF) is the most common complication following cardiac surgery, and randomised clinical trials (RCTs) and systematic reviews have been conducted to compare and evaluate different pharmacological interventions for preventing POAF. This study aimed to explore the effect of different pharmacological interventions for prophylaxis against POAF after cardiac surgery using network meta-analysis (NMA). METHODS AND ANALYSIS: A systematic search will be performed in PubMed, EMBASE and the Cochrane Library to identify RCTs, systematic reviews, meta-analyses or NMA of different pharmacological interventions for POAF. We will evaluate the risk of bias of the included RCTs according to the Cochrane Handbook V.5.1.0, and use GRADE to assess the quality of evidence. Standard pairwise meta-analysis, trial sequential analysis and Bayesian network meta-analysis will be used to compare the efficacy of different pharmacological interventions. ETHICS AND DISSEMINATION: Ethics approval and patient consent are not required as this study is a meta-analysis based on published studies. The results of this NMA and trial sequential analysis will be submitted to a peer-reviewed journal for publication. PROTOCOL REGISTRATION NUMBER: CRD42017067492.

Indexed as

Atrial FibrillationCardiac Surgical ProceduresCardiovascular AgentsPostoperative ComplicationsAdolescentAdultAgedAged, 80 and overBayes TheoremFemaleHumansMaleMiddle AgedNetwork Meta-Analysis as TopicPostoperative PeriodResearch DesignCardiovascular Agentsnetwork meta-analysispharmacological interventionspostoperative atrial fibrillation (poaf)prevention

Identifiers

PMID29289938
PMCPMC5778318
OpenAlexW2778073913

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.