Evidence map›Paper›PMID 29289937›Full record

SynthesisBMJ open2017

Effect of whole-body vibration exercise in preventing falls and fractures: a systematic review and meta-analysis.

Ditte Beck Jepsen, Katja Thomsen, Stinus Hansen, Niklas Rye Jørgensen, Tahir Masud, Jesper Ryg

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 14 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 14 syntheses or guidelines pooled it.

  1. Guideline
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  8. Does adding exercise or physical activity to pharmacological osteoporosis therapy in patients with increased fracture risk improve bone mineral density and lower fracture risk? A systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2023
    Pooled it
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  10. Guideline
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  13. European guidance for the diagnosis and management of osteoporosis in postmenopausal women.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019
    Guideline
  14. Pooled it
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  20. The combined effect of Parathyroid hormone (1-34) and whole-body Vibration exercise in the treatment of postmenopausal OSteoporosis (PaVOS study): a randomized controlled trial.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019
    Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ditte Beck JepsenDepartment of Geriatric Medicine, Odense University Hospital, Odense, Denmark.
Katja ThomsenInstitute of Clinical Research, University of Southern Denmark, Odense, Denmark.
Stinus HansenInstitute of Clinical Research, University of Southern Denmark, Odense, Denmark.
Niklas Rye JørgensenDepartment of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark.
Tahir MasudDepartment of Geriatric Medicine, Odense University Hospital, Odense, Denmark.
Jesper RygDepartment of Geriatric Medicine, Odense University Hospital, Odense, Denmark.

Funding

Low Magnitude Mechanical Stimulation to Improve BMDR01AG025489 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI KIEL, DOUGLAS P. · 2006 to 2012
$6.3M
NIA NIH HHS R01 AG025489
6 · The paper itself

Abstract

objectiveTo investigate the effect of whole-body vibration exercise (WBV) on fracture risk in adults ≥50 years of age.

designA systematic review and meta-analysis calculating relative risk ratios, fall rate ratio and absolute weighted mean difference using random effects models. Heterogeneity was estimated using I DATA SOURCES: The databases PubMed, Embase and the Cochrane Central Register from inception to April 2016 and reference lists of retrieved publications. ELIGIBILITY CRITERIA FOR SELECTING STUDIES: Randomised controlled trials examining the effect of WBV on fracture risk in adults ≥50 years of age. The primary outcomes were fractures, fall rates and the proportion of participants who fell. Secondary outcomes were bone mineral density (BMD), bone microarchitecture, bone turnover markers and calcaneal broadband attenuation (BUA).

results15 papers (14 trials) met the inclusion criteria. Only one study had fracture data reporting a non-significant fracture reduction (risk ratio (RR)=0.47, 95% CI 0.14 to 1.57, P=0.22) (moderate quality of evidence). Four studies (n=746) showed that WBV reduced the rate of falls with a rate ratio of 0.67 (95% CI 0.50 to 0.89, P=0.0006; I

conclusionsWBV reduces fall rate but seems to have no overall effect on BMD or microarchitecture. The impact of WBV on fractures requires further larger adequately powered studies. This meta-analysis suggests that WBV may prevent fractures by reducing falls. PROSPERO REGISTRATION NUMBER: CRD42016036320; Pre-results.

Indexed as

Exercise TherapyVibrationAccidental FallsAgedAged, 80 and overBone and BonesBone DensityExerciseFemaleFractures, BoneHumansMaleMiddle AgedOsteoporosis, Postmenopausalaccidental fallsexercisefracturesmeta-analysiswbvwhole-body vibration

Identifiers

PMID29289937
PMCPMC6027066

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.