Evidence map›Paper›PMID 29289757›Full record

Trial reportBiology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation2018

Tandem Autologous Hematopoietic Cell Transplantation for Patients with Primary Progressive or Recurrent Hodgkin Lymphoma: A SWOG and Blood and Marrow Transplant Clinical Trials Network Phase II Trial (SWOG S0410/BMT CTN 0703).

Eileen P Smith, Hongli Li, Jonathan W Friedberg, Louis S Constine, Lisa M Rimsza, James R Cook, Ginna G Laport, Leslie L Popplewell, Leona A Holmberg, Sonali M Smith and 4 more

Open access · hybridAbstract readClinical Trial, Phase IIMulticenter Study
In one paragraph

Trial report in Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 1 country.

Eileen P SmithHematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, California. Electronic address: esmith@coh.org.
Hongli LiSWOG Statistical Center, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Jonathan W FriedbergJames P. Wilmot Cancer Center, University of Rochester, Rochester, New York.
Louis S ConstineJames P. Wilmot Cancer Center, University of Rochester, Rochester, New York.
Lisa M RimszaDepartment of Pathology, University of Arizona, Tucson, Arizona.
James R CookMolecular Pathology, Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio.
Ginna G LaportBlood and Marrow Transplantation, Stanford University School of Medicine, Stanford, California.
Leslie L PopplewellHematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, California.
Leona A HolmbergFred Hutchinson Cancer Research Center, University of Washington and Pacific Cancer Research Consortium NCORP, Seattle, Washington.
Sonali M SmithHematology/Oncology, University of Chicago, Chicago, Illinois.
Michael LeBlancSWOG Statistical Center, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Stephen J FormanHematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, California.
Richard I FisherFox Chase Cancer Center, Temple University, Philadelphia, Pennsylvania.
Patrick J StiffHematology/Oncology, Loyola University Medical Center, Maywood, Illinois.
City Of Hope National Medical Center · USFred Hutch Cancer Center · USUniversity of Rochester · USCleveland Clinic Lerner College of Medicine · USFox Chase Cancer Center · USLoyola University Medical Center · USStanford University · USUniversity of Arizona · USUniversity of Chicago · US

Funding

SWOG Network Group Operations Center of the NCTNU10CA180888 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI PRIMO N. LARA · 2014 to 2026
$152.1M
SWOG Statistics & Data Management Center complex - extension supplement for GY06U10CA180819 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Michael L. LeBlanc · 2014 to 2026
$115.2M
Data Resource for Analyzing Blood &Marrow TransplantsU24CA076518 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI Amy M Moskop, Bronwen Shaw · 1998 to 2026
$105.2M
TUMOR SPECIFIC CYTOTOXIC T-LYMPHOCYTES IN BONE MARROW TRANSPLANTATIONP01CA049605 · NCI · STANFORD UNIVERSITY · PI David B. Miklos · 1989 to 2026
$73.3M
Blood and Marrow Transplant Clinical Trials Network DCC- The Medical College of Wisconsin, Inc.U24HL138660 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI Steven M. DeVine, Mehdi Hussain Hamadani · 2017 to 2026
$71.4M
Easy-to-read Informed Consent for HCT Clinical TrialsU10HL069294 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI HOROWITZ, MARY MARESCA · 2011 to 2016
$43.8M
The Pacific Cancer Research Consortium (PCRC), an NCORP Community SiteUG1CA189953 · NCI · SWEDISH MEDICAL CENTER, FIRST HILL · PI Alison Katherine Conlin, Charles Drescher · 2014 to 2026
$27.4M
Dayton Clinical Oncology ProgramUG1CA189957 · NCI · DAYTON CLINICAL ONCOLOGY PROGRAM · PI Howard M Gross · 2014 to 2026
$10.7M
National Community Oncology Research ProjectUG1CA189808 · NCI · VIA CHRISTI REGIONAL MEDICAL CENTER · PI DAKHIL, SHAKER R · 2014 to 2018
$8.6M
SWOG GRANT APPLICATION FOR LOYOLA UNIVERSITYU10CA046282 · NCI · LOYOLA UNIVERSITY CHICAGO · PI STIFF, PATRICK J · 1988 to 2013
$5.4M
SOUTHWEST ONCOLOGY GROUP--CLINICAL TRIALSU10CA046368 · NCI · CITY OF HOPE NATIONAL MEDICAL CENTER · PI MORTIMER, JOANNE E. · 1988 to 2013
$4.2M
UCDCCC NCTN U10 ProgramU10CA180846 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI GANDARA, DAVID R, VALICENTI, RICHARD · 2014 to 2018
$3.3M
NCI NIH HHS P01 CA049605NCI NIH HHS U10 CA046282NCI NIH HHS U10 CA046368NCI NIH HHS U10 CA180819NCI NIH HHS U10 CA180846NCI NIH HHS U10 CA180888NCI NIH HHS U24 CA076518NCI NIH HHS UG1 CA189808NCI NIH HHS UG1 CA189953NCI NIH HHS UG1 CA189957NHLBI NIH HHS U10 HL069278NHLBI NIH HHS U10 HL069291NHLBI NIH HHS U10 HL069294NHLBI NIH HHS U24 HL138660NHLBI NIH HHS UG1 HL069278NHLBI NIH HHS UG1 HL069291
6 · The paper itself

Abstract

Based on promising pilot data a phase II tandem autologous hematopoietic stem cell transplant (AHSCT) trial for relapsed/refractory Hodgkin lymphoma (HL) was performed in the US intergroup setting to determine if long-term progression-free survival (PFS) could be improved. Patients were enrolled after salvage therapy and stem cell collection. Sensitivity to salvage was defined by 1999 Standardized Response Criteria and did not include fluorodeoxyglucose-positron emission tomography. Cycle 1 consisted of melphalan 150 mg/m

Indexed as

Hematopoietic Stem Cell TransplantationAdultAgedAutograftsChildCyclophosphamideDisease-Free SurvivalEtoposideFemaleHodgkin DiseaseHumansMaleMelphalanMiddle AgedPositron-Emission TomographyRecurrenceCyclophosphamideEtoposideMelphalanAutologous stem cell transplantHodgkin lymphomaTandem transplant

Identifiers

PMID29289757
PMCPMC5965270
OpenAlexW2778424745

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.