Evidence map›Paper›PMID 29289536›Full record

ArticleBiochemical and biophysical research communications2018

Expression of PIK3IP1 in the murine uterus during early pregnancy.

Hanna E Teasley, Hye Jin Chang, Tae Hoon Kim, Bon Jeong Ku, Jae-Wook Jeong

Abstract read
In one paragraph

Article in Biochemical and biophysical research communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Hanna E TeasleyDepartment of Obstetrics, Gynecology & Reproductive Biology, Michigan State University, College of Human Medicine, Grand Rapids, MI 49503, USA; Department of Biology, Kalamazoo College, Kalamazoo, MI, USA.
Hye Jin ChangDepartment of Obstetrics, Gynecology & Reproductive Biology, Michigan State University, College of Human Medicine, Grand Rapids, MI 49503, USA; Health Promotion Center, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Tae Hoon KimDepartment of Obstetrics, Gynecology & Reproductive Biology, Michigan State University, College of Human Medicine, Grand Rapids, MI 49503, USA.
Bon Jeong KuDepartment of Internal Medicine, Chungnam National University College of Medicine, Daejeon, Republic of Korea. Electronic address: bonjeong@cnu.ac.kr.
Jae-Wook JeongDepartment of Obstetrics, Gynecology & Reproductive Biology, Michigan State University, College of Human Medicine, Grand Rapids, MI 49503, USA. Electronic address: jeongj@msu.edu.
Michigan State University · USChungnam National University · KRKalamazoo College · USSeoul National University Bundang Hospital · KR

Funding

Risk factors for early pregnancy lossR01HD084478 · NICHD · MICHIGAN STATE UNIVERSITY · PI JEONG, JAE-WOOK · 2016 to 2020
$1.6M
NICHD NIH HHS R01 HD084478
6 · The paper itself

Abstract

The ovarian steroid hormones, estrogen (E2) and progesterone (P4), are essential regulators of uterine functions necessary for development, embryo implantation, and normal pregnancy. ARID1A plays an important role in steroid hormone signaling in endometrial function and pregnancy. In previous studies, using high density DNA microarray analysis, we identified phosphatidylinositol-3-kinase interacting protein 1 (Pik3ip1) as one of the genes up-regulated by ARID1A. In the present study, we performed real-time qPCR and immunohistochemistry analysis to investigate the regulation of PIK3IP1 by ARID1A and determine expression patterns of PIK3IP1 in the uterus during early pregnancy. The expression of PIK3IP1 was strong at the uterine epithelial and stromal cells of the control mice. However, expression of PIK3IP1 was remarkably reduced in the Pgr

Indexed as

AnimalsCarrier ProteinsDNA-Binding ProteinsEmbryonic DevelopmentFemaleGene Expression Regulation, DevelopmentalIntracellular Signaling Peptides and ProteinsMembrane ProteinsMiceNuclear ProteinsPregnancyPregnancy, AnimalReceptors, ProgesteroneTissue DistributionTranscription FactorsUterusArid1a protein, mouseCarrier ProteinsDNA-Binding ProteinsIntracellular Signaling Peptides and ProteinsMembrane ProteinsNuclear ProteinsPik3ip1 protein, mouseReceptors, ProgesteroneTranscription FactorsARID1APIK3IP1Progesterone receptorUterus

Identifiers

PMID29289536
PMCPMC5762254
OpenAlexW2781459077

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.